ILF2
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Official Full Name
interleukin enhancer binding factor 2, 45kDa -
Overview
Nuclear factor of activated T-cells (NFAT) is a transcription factor required for T-cell expression of the interleukin 2 gene. NFAT binds to a sequence in the interleukin 2 gene enhancer known as the antigen receptor response element 2. In addition, NFAT can bind RNA and is an essential component for encapsidation and protein priming of hepatitis B viral polymerase. NFAT is a heterodimer of 45 kDa and 90 kDa proteins, the smaller of which is the product of this gene. The encoded protein binds strongly to the 90 kDa protein and stimulates its ability to enhance gene expression. -
Synonyms
ILF2;interleukin enhancer binding factor 2, 45kDa;interleukin enhancer binding factor 2, 45kD;interleukin enhancer-binding factor 2;NF45;nuclear factor of activated T-cells 45 kDa;nuclear factor of activated T-cells, 45-kDa;PRO3063;MGC8391
Recombinant Proteins
- Human
- Zebrafish
- Rhesus macaque
- Rat
- Mouse
- E.coli
- Mammalian Cells
- HEK293
- Wheat Germ
- In Vitro Cell Free System
- His
- Non
- His&Fc&Avi
- Flag
- Myc&DDK
- GST
Involved Pathway
ILF2 involved in several pathways and played different roles in them. We selected most pathways ILF2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with ILF2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
ILF2 has several biochemical functions, for example, ATP binding,DNA binding,double-stranded RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ILF2 itself. We selected most functions ILF2 had, and list some proteins which have the same functions with ILF2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| DNA binding | FOXO1B,ZBTB8A,RNF11,PHTF1,ZFP93,MYCLA,NR2F6B,NR4A3,CENPA,EME1 |
| double-stranded RNA binding | OAS3,LSM14A,OAS1B,ADARB1,OASL,MSN,AGO3,ZNF346,SLC3A2,DDX21 |
| ATP binding | MYH1E,QRSL1,DDX19,OASL2,NLRC4,MOK,TAF1,DDX3X,TYRO3,RUVBL2 |
| poly(A) RNA binding | RBM4B,EIF5B,MECP2,DYNC1LI1,HHATL,EIF4A1,FAM46A,DNTTIP2,TBL3,WDR43 |
| protein binding | ZNF317,FANCA,MAPK6,AKAP13,TNFAIP8L2,EPO,MFAP1,KCTD5,MUS81,CRTAC1 |
| transferase activity | ZDHHC18B,ZDHHC16,Aatk,Art2b,FUT9A,ACVR2AA,ACVR1L,AGPAT9L,EHMT1A,EPHB4B |
Interacting Protein
ILF2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ILF2 here. Most of them are supplied by our site. Hope this information will be useful for your research of ILF2.
YBX1;ILF3;PPID;VCAM1
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References
- Marchesini, M; Storti, P; et al. ILF2 Is a Regulator of RNA Splicing and DNA Damage Response in 1q21-Amplified Multiple Myeloma. BLOOD 124:-(2014).
- Cardenas, G; Fragoso, G; et al. Neurocysticercosis: the effectiveness of the cysticidal treatment could be influenced by the host immunity. MEDICAL MICROBIOLOGY AND IMMUNOLOGY 203:373-381(2014).
