IFIT3
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Official Full Name
interferon-induced protein with tetratricopeptide repeats 3 -
Overview
Interferon-induced protein with tetratricopeptide repeats 3 is a protein that in humans is encoded by the IFIT3 gene. -
Synonyms
IFIT3;interferon-induced protein with tetratricopeptide repeats 3;IFIT4, interferon induced protein with tetratricopeptide repeats 4;CIG 49;GARG 49;IFI60;IRG2;ISG60;RIG G;RP11-149I23.4;CIG49;IFI-60K;IFI60K;IFIT-3;IFIT-4;IFIT3_HUMAN;IFIT4;Interferon induced 60 kDa protein;Interferon induced protein with tetratricopeptide repeats 3;Interferon-induced 60 kDa protein;Interferon-induced protein with tetratricopeptide repeats 4;ISG-60;Retinoic acid induced gene G protein;Retinoic acid-induced gene G protein;RIG-G;RIGG;CIG-49;GARG-49
Recombinant Proteins
- Human
- E.coli
- HEK293
- Mammalian Cells
- GST
- His
- Non
- His&Fc&Avi
- Flag
- Myc&DDK
- His&SUMO
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| IFIT3-14069H | Recombinant Human IFIT3, GST-tagged | E.coli | Human | GST | 141-490a.a. | |
| IFIT3-94H | Recombinant Human IFIT3, His-tagged | E.coli | Human | His |
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| IFIT3-5285HCL | Recombinant Human IFIT3 293 Cell Lysate | HEK293 | Human | Non |
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| IFIT3-5286HCL | Recombinant Human IFIT3 293 Cell Lysate | HEK293 | Human | Non |
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| IFIT3-1145H | Recombinant Human IFIT3 Protein, His (Fc)-Avi-tagged | HEK293 | Human | His&Fc&Avi |
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| IFIT3-1145H-B | Recombinant Human IFIT3 Protein Pre-coupled Magnetic Beads | HEK293 | Human |
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| IFIT3-1290HFL | Recombinant Full Length Human IFIT3 Protein, C-Flag-tagged | Mammalian Cells | Human | Flag | Full L. |
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| IFIT3-2450H | Recombinant Human IFIT3 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293 | Human | Myc&DDK |
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| IFIT3-3066H | Recombinant Human IFIT3 protein, His-SUMO-tagged | E.coli | Human | His&SUMO | 1-490aa |
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Involved Pathway
IFIT3 involved in several pathways and played different roles in them. We selected most pathways IFIT3 participated on our site, such as Cytokine Signaling in Immune system,Immune System,Interferon Signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with IFIT3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Interferon Signaling | ARIH1,IRF6,TRIM68,IFIT10,XAF1,IFITM2,IRF9,IFI27,TRIM3,BST2 |
| Cytokine Signaling in Immune system | DUSP10,SPTB,USP18,PHB,TNFRSF13C,UBE2V1,CRKL,IFITM3,EIF4E3,IRF9 |
| Immune System | IFIT11,IFITM3,PJA1,FBXO44,EIF4G2,SLAMF6,KIF3C,XAF1,LAIR1,OSBPL1A |
| Interferon alpha/beta signaling | OASL,GBP2,USP18,ISG20,SAMHD1,IRF4,IRF9,IRF6,IRF2,IFI6 |
Protein Function
IFIT3 has several biochemical functions, for example, RNA binding,identical protein binding,molecular_function. Some of the functions are cooperated with other proteins, some of the functions could acted by IFIT3 itself. We selected most functions IFIT3 had, and list some proteins which have the same functions with IFIT3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| identical protein binding | FRS3,DAPK3,NUFIP1,WAS,ORAI1,HOOK1,HTT,Serpina1b,FHIT,NLRC4 |
| RNA binding | MRPL23,HNRNPL,QKIA,TERT,RNASET2,TTC6,RBM39B,HNRNPH1,EXOSC1,RC3H2 |
| molecular_function | KIAA0430,CRYGM2D11,ZNF486,BTBD17,PRPF38A,MN1,RPL41,TAPT1,DEFB39,KIF12 |
| protein binding | DENND2D,SCARA3,DGKZ,PPP1R12B,HIST1H2BE,CEP152,LRDD,ZFP259,CBL,PIM1 |
Interacting Protein
IFIT3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IFIT3 here. Most of them are supplied by our site. Hope this information will be useful for your research of IFIT3.
Resources
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References
- Schmeisser, H; Mejido, J; et al. Identification of Alpha Interferon-Induced Genes Associated with Antiviral Activity in Daudi Cells and Characterization of IFIT3 as a Novel Antiviral Gene. JOURNAL OF VIROLOGY 84:10671-10680(2010).
- Serrano-Fernandez, P; Moller, S; et al. Time course transcriptomics of IFNB1b drug therapy in multiple sclerosis. AUTOIMMUNITY 43:172-178(2010).
