ICT1
-
Official Full Name
immature colon carcinoma transcript 1 -
Overview
The adult colon epithelium contains 3 differentiated cell types that arise from a multipotent stem cell. Deviation from the normal maturation pathway by neoplastic transformation is thought to initiate in stem cells or their early descendants. One potential marker is ICT1 whose mRNA and protein were more highly expressed in undifferentiated than in differentiated cells. -
Synonyms
ICT1;immature colon carcinoma transcript 1;peptidyl-tRNA hydrolase ICT1, mitochondrial;DS 1;Digestion substraction 1;DS1;Immature colon carcinoma transcript 1 protein;DS-1
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| ICT1-395H | Recombinant Human immature colon carcinoma transcript 1, His-tagged | E.coli | Human | His | 30-206 a.a. |
|
| ICT1-7978M | Recombinant Mouse ICT1 Protein | Mammalian Cells | Mouse | His |
|
|
| ICT1-5313HCL | Recombinant Human ICT1 293 Cell Lysate | HEK293 | Human | Non |
|
|
| ICT1-4369H | Recombinant Human ICT1 protein, His-SUMO-tagged | E.coli | Human | His&SUMO | 30-206aa |
|
| ICT1-4405M | Recombinant Mouse ICT1 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
|
|
| ICT1-4405M-B | Recombinant Mouse ICT1 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
|
Involved Pathway
ICT1 involved in several pathways and played different roles in them. We selected most pathways ICT1 participated on our site, such as Mitochondrial translation,Mitochondrial translation elongation,Mitochondrial translation initiation, which may be useful for your reference. Also, other proteins which involved in the same pathway with ICT1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Mitochondrial translation | MRPS28,MRPL41,DAP3,MRRF,MRPL40,MRPL48,MRPS33,MRPL37,TUFM,MRPL55 |
| Organelle biogenesis and maintenance | MRPS26,TTC26,TNPO1,TSFM,TCTEX1D1,KIF17,C10orf2,CNGA2,RAB3IP,MRPL45 |
| Mitochondrial translation initiation | MRPL54,MRPS26,MRPS25,MRPL44,MRPL41,MRPS35,MRPL39,AURKAIP1,MRPL46,DAP3 |
| Mitochondrial translation termination | MRPL51,DAP3,PTCD3,MRPS24,MRPS35,MRPL54,MRPL47,MRPS26,MRPL49,GFM2 |
| Mitochondrial translation elongation | MRPL37,AURKAIP1,MRPL3,MRPL51,MRPL41,MRPL10,MRPL42,MRPL28,MRPS26,MRPL55 |
Protein Function
ICT1 has several biochemical functions, for example, aminoacyl-tRNA hydrolase activity,ribosome binding,translation release factor activity, codon nonspecific. Some of the functions are cooperated with other proteins, some of the functions could acted by ICT1 itself. We selected most functions ICT1 had, and list some proteins which have the same functions with ICT1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| translation release factor activity, codon nonspecific | C12orf65 |
| NOT translation release factor activity, codon specific | C12orf65 |
| ribosome binding | RPN2,NARG1,EIF5A2,ERI1,CPEB3,ETF1,ETF1B,NAA16,YTHDF1,C12orf65 |
| aminoacyl-tRNA hydrolase activity | PTRH1,C12orf65,PTRHD1,PTRH2 |
Interacting Protein
ICT1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ICT1 here. Most of them are supplied by our site. Hope this information will be useful for your research of ICT1.
MRPL3;DAP3;MRPL12;MCC;VHL;GTPBP10;MRPL38;a6nle7_human;grsf1;slc25a6;nipsnap1;sdha;oxa1l;mrps31;immt
Resources
Related Services
Related Products
References
