HTR3B

  • Official Full Name

    5-hydroxytryptamine (serotonin) receptor 3B

  • Overview

    The product of this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit B of;the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a;hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. It is not;functional as a homomeric complex, but a pentaheteromeric complex with subunit A (HTR3A) displays the full functional;features of this receptor.

  • Synonyms

    HTR3B;5-hydroxytryptamine (serotonin) receptor 3B;5-hydroxytryptamine receptor 3B;5 HT3B;5 HT3 B;5 HTR3B;5 hydroxytryptamine 3 receptor B subunit;5 hydroxytryptamine receptor 3B;5 hydroxytryptamine serotonin receptor 3B;5-HT3-B;5-HT3B;5-HTR3B;5-hydroxytryptamine 3 receptor B subunit;5-hydroxytryptamine serotonin receptor 3B;5HT3B_HUMAN;5HTR3B;Serotonin gated ion channel subunit;serotonin receptor 3B;serotonin-gated ion channel subunit

Recombinant Proteins

  • Rat
  • Mouse
  • Human
  • Mus musculus
  • Mammalian Cell
  • HEK293
  • Wheat Germ
  • In Vitro Cell Free System
  • E.coli expression system
  • His
  • Non
  • His&Fc&Avi
Cat.# Product name Source (Host) Species Tag Protein Length Price
HTR3B-2966R Recombinant Rat HTR3B Protein Mammalian Cell Rat His
HTR3B-7936M Recombinant Mouse HTR3B Protein Mammalian Cell Mouse His
HTR3B-828HCL Recombinant Human HTR3B cell lysate Human Non
HTR3B-2621R Recombinant Rat HTR3B Protein, His (Fc)-Avi-tagged HEK293 Rat His&Fc&Avi
HTR3B-2621R-B Recombinant Rat HTR3B Protein Pre-coupled Magnetic Beads HEK293 Rat
HTR3B-4377M Recombinant Mouse HTR3B Protein, His (Fc)-Avi-tagged HEK293 Mouse His&Fc&Avi
HTR3B-4377M-B Recombinant Mouse HTR3B Protein Pre-coupled Magnetic Beads HEK293 Mouse
HTR3B-5239H Recombinant Human HTR3B Protein Wheat Germ Human Non
HTR3B-5693HF Recombinant Full Length Human HTR3B Protein In Vitro Cell Free System Human Full L. 172 amino acids
RFL1854MF Recombinant Full Length Mouse 5-Hydroxytryptamine Receptor 3B(Htr3B) Protein, His-Tagged E.coli expression system Mus musculus His Full L. Full Length of Mature Protein (22-437)
RFL20927HF Recombinant Full Length Human 5-Hydroxytryptamine Receptor 3B(Htr3B) Protein, His-Tagged E.coli expression system Human His Full L. Full Length of Mature Protein (22-441)
RFL5589RF Recombinant Full Length Rat 5-Hydroxytryptamine Receptor 3B(Htr3B) Protein, His-Tagged E.coli expression system Rat His Full L. Full Length of Mature Protein (22-437)

    Involved Pathway

    HTR3B involved in several pathways and played different roles in them. We selected most pathways HTR3B participated on our site, such as Serotonergic synapse, which may be useful for your reference. Also, other proteins which involved in the same pathway with HTR3B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Serotonergic synapse MAPK1,HTR3C,CYP2C37,HTR1E,BRAF,GNGT1,PLA2G4A,SLC18A1,PLCB4,PLCB2

    Protein Function

    HTR3B has several biochemical functions, for example, NOT contributes_to acetylcholine binding,NOT contributes_to acetylcholine receptor activity,NOT contributes_to acetylcholine-activated cation-selective channel activity. Some of the functions are cooperated with other proteins, some of the functions could acted by HTR3B itself. We selected most functions HTR3B had, and list some proteins which have the same functions with HTR3B. You can find most of the proteins on our site.

    Function Related Protein
    serotonin receptor activity HTR3E,HTR5AL,HTR1D,HTR3C,HTR2C,HTR5A,HTR1B,HTR4,HTR2B,HTR7
    NOT contributes_to acetylcholine-activated cation-selective channel activity HTR3A,HTR3C,HTR3E
    serotonin-activated cation-selective channel activity HTR3C,HTR3E,HTR3A
    NOT contributes_to acetylcholine receptor activity HTR3C,HTR3A,HTR3E
    ion channel activity FXYD6,Chrng,TRPC5A,P2RX4A,NALCN,TRPM1B,KCNK3,SCN4AA,KCNH1A,CACNA1DA
    NOT contributes_to acetylcholine binding HTR3C,HTR3E,HTR3A

    Interacting Protein

    HTR3B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HTR3B here. Most of them are supplied by our site. Hope this information will be useful for your research of HTR3B.

    HTR3A

    Resources

    Research Area

    5-HT Receptors

    References

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