HPCAL4
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Official Full Name
hippocalcin like 4 -
Overview
The protein encoded by this gene is highly similar to human hippocalcin protein and hippocalcin like-1 protein. It also has similarity to rat neural visinin-like Ca2+-binding protein-type 1 and 2 proteins. This encoded protein may be involved in the calcium-dependent regulation of rhodopsin phosphorylation. The transcript of this gene has multiple polyadenylation sites. -
Synonyms
HPCAL4;hippocalcin like 4;hippocalcin-like protein 4;DKFZp761G122;HLP4;Hippocalcin like protein 4;HPCL4_HUMAN;OTTHUMP00000010835
Recombinant Proteins
- Human
- Rat
- Zebrafish
- Mouse
- E.coli
- Mammalian Cells
- Wheat Germ
- HEK293
- In Vitro Cell Free System
- GST
- His
- Non
- T7
- Avi
- Fc
- DDK
- Myc
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| HPCAL4-13919H | Recombinant Human HPCAL4, GST-tagged | E.coli | Human | GST | 1-191a.a. | |
| HPCAL4-2899R | Recombinant Rat HPCAL4 Protein | Mammalian Cells | Rat | His |
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| HPCAL4-5005H | Recombinant Human HPCAL4 Protein, GST-tagged | Wheat Germ | Human | GST |
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| HPCAL4-6463Z | Recombinant Zebrafish HPCAL4 | Mammalian Cells | Zebrafish | His |
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| HPCAL4-5405HCL | Recombinant Human HPCAL4 293 Cell Lysate | HEK293 | Human | Non |
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| HPCAL4-1741H | Recombinant Human HPCAL4 protein, His & T7-tagged | E.coli | Human | His&T7 | Gly2~Lys191 (Accession # Q9UM19) |
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| HPCAL4-2554R | Recombinant Rat HPCAL4 Protein, His (Fc)-Avi-tagged | HEK293 | Rat | Avi&Fc&His |
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| HPCAL4-2554R-B | Recombinant Rat HPCAL4 Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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| Hpcal4-3433M | Recombinant Mouse Hpcal4 Protein, Myc/DDK-tagged | HEK293 | Mouse | DDK&Myc |
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| HPCAL4-3620HF | Recombinant Full Length Human HPCAL4 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 191 amino acids |
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Involved Pathway
HPCAL4 involved in several pathways and played different roles in them. We selected most pathways HPCAL4 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with HPCAL4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
HPCAL4 has several biochemical functions, for example, calcium channel regulator activity,calcium ion binding,protein C-terminus binding. Some of the functions are cooperated with other proteins, some of the functions could acted by HPCAL4 itself. We selected most functions HPCAL4 had, and list some proteins which have the same functions with HPCAL4. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | MPPED2,PTPN14,LTBP1,Akap3,STUB1,PEF1,SUMO2,PRKAR2AA,ATF3,ERAL1 |
| calcium ion binding | TBC1D9B,CABP2,CALM2,LDLR,MYL2,PCDH15B,PCDHB13,FSTL4,ANXA4,PCDH19 |
| protein C-terminus binding | FOXN3,PIAS3,CEP135,SDC1,LIG4,CDC20,YWHAQ,SNF8,SLC4A1,CLIC6 |
| calcium channel regulator activity | NPY,TSPAN13B,NRXN3,CACNA2D2,GRM3,TMEM110,GNB2,CACNA2D1A,NRXN2,CACNA2D4 |
| protein domain specific binding | CASP2,HIST1H4H,HNRNPM,MPP7,EZR,NDE1,HOMER3,WNT5A,TFDP2,VPS11 |
Interacting Protein
HPCAL4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HPCAL4 here. Most of them are supplied by our site. Hope this information will be useful for your research of HPCAL4.
DTX2;FAM131C;TTC12;tir;UBE3A;DTX2;TSC22D3
Resources
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References
- Ilies, I; Zupanc, MM; et al. PROTEOME ANALYSIS REVEALS PROTEIN CANDIDATES INVOLVED IN EARLY STAGES OF BRAIN REGENERATION OF TELEOST FISH. NEUROSCIENCE 219:302-313(2012).
- Tang, WY; Morey, LM; et al. Neonatal Exposure to Estradiol/Bisphenol A Alters Promoter Methylation and Expression of Nsbp1 and Hpcal1 Genes and Transcriptional Programs of Dnmt3a/b and Mbd2/4 in the RatProstate Gland Throughout Life. ENDOCRINOLOGY 153:42-55(2012).
