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HOXD1

Official Full Name

homeobox D1
Overview

This gene is a member of the Antp homeobox family and encodes a protein with a homeobox DNA-binding domain. This nuclear protein functions as a sequence-specific transcription factor that is involved in differentiation and limb development. Mutations in this gene have been associated with severe developmental defects on the anterior-posterior (a-p) limb axis.
Synonyms

HOXD1; homeobox D1; homeo box D1 , HOX4, HOX4G; homeobox protein Hox-D1; homeo box 4G; homeo box D1; Homeobox protein Hox D1; Homeobox protein Hox-GG; HOX 4; HOX 4G; HOX D1; Hox-4.7; HOX4; Hox4.9; HOX4G; HXD1_HUMAN; OTTHUMP00000163336;

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	HOXD1-26895TH	Recombinant Human HOXD1	Wheat Germ	Non	90 amino acids	Inquiry
Human	HOXD1-4988H	Recombinant Human HOXD1 Protein, GST-tagged	Wheat Germ	GST		Inquiry
Human	HOXD1-5413HCL	Recombinant Human HOXD1 293 Cell Lysate	HEK293	Non		Inquiry
Human	HOXD1-3731HF	Recombinant Full Length Human HOXD1 Protein, GST-tagged	In Vitro Cell Free System	GST	328 amino acids	Inquiry

Involved Pathway
Protein Function
Interacting Protein
Other Resource

HOXD1 involved in several pathways and played different roles in them. We selected most pathways HOXD1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with HOXD1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

HOXD1 has several biochemical functions, for example, sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by HOXD1 itself. We selected most functions HOXD1 had, and list some proteins which have the same functions with HOXD1. You can find most of the proteins on our site.

Function	Related Protein
sequence-specific DNA binding	ZNF831;GATA4;SIX4B;EMX1;NR0B1;SIX1B;HOXA2B;DRGX;HOXC12A

HOXD1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HOXD1 here. Most of them are supplied by our site. Hope this information will be useful for your research of HOXD1.

Research Area

de Groot, JS; Pan, XJ; et al. Validation of DNA promoter hypermethylation biomarkers in breast cancer - a short report. CELLULAR ONCOLOGY 37:297-303(2014).

Mori, Y; Saito, T; et al. Identification of Fibroblast Growth Factor-18 as a Molecule to Protect Adult Articular Cartilage by Gene Expression Profiling*. JOURNAL OF BIOLOGICAL CHEMISTRY 289:10192-10200(2014).