HAUS2
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Official Full Name
HAUS augmin-like complex, subunit 2 -
Overview
HAUS2 is 1 of 8 subunits of the 390-kD human augmin complex, or HAUS complex. The augmin complex was first identified;in Drosophila, and its name comes from the Latin verb augmentare, meaning to increase. The augmin complex is a;microtubule-binding complex involved in microtubule generation within the mitotic spindle and is vital to mitotic;spindle assembly (Goshima et al., 2008 (PubMed 18443220); Uehara et al., 2009 (PubMed 19369198)). -
Synonyms
HAUS2;HAUS augmin-like complex, subunit 2;C15orf25, centrosomal protein 27kDa , CEP27, chromosome 15 open reading frame 25;HAUS augmin-like complex subunit 2;FLJ10460;HsT17025;C15orf25;Centrosomal protein 27 kDa;Chromosome 15 open reading frame 25;centrosomal protein 27kDa;centrosomal protein of 27 kDa;CEP27
Recombinant Proteins
- Rhesus macaque
- Chicken
- Human
- Mouse
- Mammalian Cells
- Wheat Germ
- HEK293
- In Vitro Cell Free System
- E.coli
- His
- GST
- Non
- Avi
- Fc
Involved Pathway
HAUS2 involved in several pathways and played different roles in them. We selected most pathways HAUS2 participated on our site, such as Anchoring of the basal body to the plasma membrane,Assembly of the primary cilium,Cell Cycle, which may be useful for your reference. Also, other proteins which involved in the same pathway with HAUS2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Cell cycle | SGOL1,SET,CDK6,VRK1,MCPH1,CCNB3,BRE,NCAPD2,USO1,CEP135 |
| Loss of proteins required for interphase microtubule organizationfrom the centrosome | NEDD1,TUBG1,MAPRE1,CEP78,CEP70,CEP76,TSGA14,SSNA1,ODF2B,CEP164 |
| Anchoring of the basal body to the plasma membrane | NPHP4,DCTN1,TMEM216,CEP63,CKAP5,CETN2,CLASP1A,CEP76,CEP70,AKAP9 |
| Cell Cycle, Mitotic | ENSAB,CDK5RAP2,CEP78,CENPC1,AHCTF1,ACTR1A,DPF1,RCC2,CDKN2C,TUBGCP2 |
| Centrosome maturation | TUBGCP4,CEP290,CP110,CEP135,TUBB4B,CCP110,CDK11B,CLASP1A,CEP152,FGFR1OP |
| Assembly of the primary cilium | TTC30A,BBS10,DYNLL2B,BBS12,NDE1,TCTN1,NEK2,DYNC1H1,PROL1,DYNLRB1 |
| G2/M Transition | OFD1,TUBGCP4,CEP290,CEP72,DYNC1I2,CEP78,TUBG2,LIN52,DYNC1H1,ODF2B |
| Loss of Nlp from mitotic centrosomes | SSNA1,CEP78,CEP290,CEP70,CKAP5,TUBG1,NINL,ODF2,DCTN1A,PLK4 |
Protein Function
HAUS2 has several biochemical functions, for example, molecular_function. Some of the functions are cooperated with other proteins, some of the functions could acted by HAUS2 itself. We selected most functions HAUS2 had, and list some proteins which have the same functions with HAUS2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| molecular_function | CCDC40,Armc3,LRP3,DCAF12L1,GAGE7,CLDN22,TMEM88B,JRKL,SERF1A,CUEDC1B |
Interacting Protein
HAUS2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HAUS2 here. Most of them are supplied by our site. Hope this information will be useful for your research of HAUS2.
Haus4;Haus1;HAUS5;HAUS3;HAUS6;HAUS1;HAUS7;HAUS8;HAUS4;Haus6;MAPK6
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