GUCY2F
-
Official Full Name
guanylate cyclase 2F, retinal -
Overview
The protein encoded by this gene is a guanylyl cyclase found predominantly in photoreceptors in the retina. The encoded protein is thought to be involved in resynthesis of cGMP after light activation of the visual signal transduction cascade, allowing a return to the dark state. This protein is a single-pass type I membrane protein. Defects in this gene may be a cause of X-linked retinitis pigmentosa. -
Synonyms
GUCY2F;guanylate cyclase 2F, retinal;retinal guanylyl cyclase 2;CYGF;GC F;guanylate cyclase 2D like;membrane (retina specific);GUC2DL;RetGC 2;ROS GC2;guanylate cyclase F;rod outer segment membrane guanylate cyclase 2;guanylate cyclase 2D-like,
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| GUCY2F-0406H | Recombinant Human GUCY2F protein, His-tagged | E.coli | Human | His | 71-398 aa | |
| GUCY2F-2759R | Recombinant Rat GUCY2F Protein | Mammalian Cell | Rat | His |
|
|
| GUCY2F-4494H | Recombinant Human GUCY2F Protein, GST-tagged | Wheat Germ | Human | GST |
|
|
| GUCY2F-9369Z | Recombinant Zebrafish GUCY2F | Mammalian Cell | Zebrafish | His |
|
|
| GUCY2F-2413R | Recombinant Rat GUCY2F Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
|
|
| GUCY2F-2413R-B | Recombinant Rat GUCY2F Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
|
Involved Pathway
GUCY2F involved in several pathways and played different roles in them. We selected most pathways GUCY2F participated on our site, such as Purine metabolism,Phototransduction, which may be useful for your reference. Also, other proteins which involved in the same pathway with GUCY2F were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Purine metabolism | POLA1,URAD,PKM,ADKA,NUDT2,POLR2K,PAICS,NME7,AMPD3B,PDE6D |
| Phototransduction | GUCA1C,CALM1,RCV1,SLC24A1,CALM3A,GNGT1,CALM3B,CALM3,CALM2B,GUCA1D |
Protein Function
GUCY2F has several biochemical functions, for example, ATP binding,NOT adenylate cyclase activity,guanylate cyclase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GUCY2F itself. We selected most functions GUCY2F had, and list some proteins which have the same functions with GUCY2F. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| lyase activity | THNSL2,MOCOS,ADCY1B,ALDOCA,ALDOAA,CTHL,CAR7,IRG1L,THA1,TYW1 |
| protein kinase activity | POMK,PAN3,EIF2AK3,SGK2A,CDK17,INSRA,MAP3K14,GC3,EGFRA,IKBKB |
| phosphorus-oxygen lyase activity | GUCY2E,ADCY2B,BST1,GC2,ADCY1A,NPR1A,GC3,CD38,ADCY1B |
| nucleotide binding | RHOAA,YTHDC2,RAB25B,SNRNP70,ZNF638,TNIKB,DYRK1AA,PABPC1A,MYO10,RALAA |
| ATP binding | CERK,RPS6KB1,ABCC9,GM711,DGKZ,RAD54L,SYN1,OLA1,NME6,NLRP7 |
| NOT adenylate cyclase activity | GUCY1A3,GUCY2C,NPR1A,GUCY1B3,GC3,NPR2,GC2,NPR3,NPR1 |
| guanylate cyclase activity | GUCY2E,NPR1A,NPR1,GUCY2C,GUCY1A3,GC2,GC3,GUCY1B3,NPR2 |
Interacting Protein
GUCY2F has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GUCY2F here. Most of them are supplied by our site. Hope this information will be useful for your research of GUCY2F.
Resources
Related Services
Related Products
References
