GUCY2D

  • Official Full Name

    guanylate cyclase 2D, membrane (retina-specific)

  • Overview

    This gene encodes a retina-specific guanylate cyclase, which is a member of the membrane guanylyl cyclase family. Like other membrane guanylyl cyclases, this enzyme has a hydrophobic amino-terminal signal sequence followed by a large extracellular domain, a single membrane spanning domain, a kinase homology domain, and a guanylyl cyclase catalytic domain. In contrast to other membrane guanylyl cyclases, this enzyme is not activated by natriuretic peptides. Mutations in this gene result in Leber congenital amaurosis and cone-rod dystrophy-6 diseases.

  • Synonyms

    GUCY2D;guanylate cyclase 2D, membrane (retina-specific);cone rod dystrophy 5/6 , CORD5, CORD6, GUC1A4, GUC2D, LCA;retinal guanylyl cyclase 1;CYGD;LCA1;retGC;RETGC 1;ROS GC1;CORD6;guanylate cyclase 2D membrane (retina-specific);GUC1A4;GUC2D;LCA;RETGC-1;ROS-GC1;ROS-GC;OTTHUMP00000135309;guanylate cyclase 2D, retinal;rod outer segment membrane guanylate cyclase;RCD2;CORD5;ROSGC

Recombinant Proteins

  • Rat
  • Human
  • Mammalian Cells
  • Wheat Germ
  • HEK293
  • His
  • GST
  • His&Fc&Avi
  • His&Avi
  • Flag
  • Myc&DDK

    Involved Pathway

    GUCY2D involved in several pathways and played different roles in them. We selected most pathways GUCY2D participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with GUCY2D were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    Protein Function

    GUCY2D has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by GUCY2D itself. We selected most functions GUCY2D had, and list some proteins which have the same functions with GUCY2D. You can find most of the proteins on our site.

    Function Related Protein

    Interacting Protein

    GUCY2D has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GUCY2D here. Most of them are supplied by our site. Hope this information will be useful for your research of GUCY2D.

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