GSTO2

  • Official Full Name

    glutathione S-transferase omega 2
  • Overview

    The protein encoded by this gene is an omega class glutathione S-transferase (GST). GSTs are involved in the metabolism of xenobiotics and carcinogens. Four transcript variants encoding different isoforms have been found for this gene.
  • Synonyms

    GSTO2;glutathione S-transferase omega 2;glutathione S-transferase omega-2;bA127L20.1;Glutathione S transferase like protein;Glutathione S transferase omega 2;GSTO 2;GSTO-2;GSTO2_HUMAN;glutathione-S-transferase-like protein;bA127L20.1 (novel glutathione-S-transferase)

Recombinant Proteins

  • Human
  • Zebrafish
  • Rhesus macaque
  • E.coli
  • Mammalian Cells
  • Wheat Germ
  • HEK293
  • In Vitro Cell Free System
  • His
  • GST
  • Non
  • Avi
  • Fc
  • DDK
  • Myc
Cat.# Product name Source (Host) Species Tag Protein Length Price
GSTO2-15855H Recombinant Human GSTO2, His-tagged E.coli Human His 1-243aa
GSTO2-1759Z Recombinant Zebrafish GSTO2 Mammalian Cells Zebrafish His
GSTO2-1961H Recombinant Human Glutathione S-Transferase Omega 2, His-tagged E.coli Human His
GSTO2-1996R Recombinant Rhesus monkey GSTO2 Protein, His-tagged Mammalian Cells Rhesus macaque His
GSTO2-4426H Recombinant Human GSTO2 Protein, GST-tagged Wheat Germ Human GST
GSTO2-5710HCL Recombinant Human GSTO2 293 Cell Lysate HEK293 Human Non
GSTO2-1817R Recombinant Rhesus Macaque GSTO2 Protein, His (Fc)-Avi-tagged HEK293 Rhesus macaque Avi&Fc&His
GSTO2-1817R-B Recombinant Rhesus Macaque GSTO2 Protein Pre-coupled Magnetic Beads HEK293 Rhesus macaque
GSTO2-3229H Recombinant Human GSTO2 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293 Human DDK&Myc
GSTO2-3366HF Recombinant Full Length Human GSTO2 Protein, GST-tagged In Vitro Cell Free System Human GST Full L. 243 amino acids

    Involved Pathway

    GSTO2 involved in several pathways and played different roles in them. We selected most pathways GSTO2 participated on our site, such as Biological oxidations,Chemical carcinogenesis,Drug metabolism - cytochrome P450, which may be useful for your reference. Also, other proteins which involved in the same pathway with GSTO2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Biological oxidations FDX1,SLC35B3,CYP4F11,NCOA2,CYP2AD3,AHCY,CYP2K6,UGT1B7,UGT1B4,UGT1B2
    Chemical carcinogenesis CYP2A6,CYP2C8,CYP1A1,ADH7,AHA-1,CYP1B1,MGST1,MGST2,CYP3A7,CYP3A25
    Metabolism KCNC2,MMADHC,CA5B,ADH8B,UGT1B1,ACOT11A,ARSK,PTPMT1,SURF1,STARD5
    Glutathione conjugation GGT6,GGTLC1,GSTK1,AKR1A1
    Metabolism of vitamins and cofactors GPHNA,SLC2A3,SLC25A16,SLC46A1,CTRC,SLC5A6B,NAMPT,MMADHC,PDZD11,ELA2L
    Drug metabolism - cytochrome P450 ADH1B,ADH6,CYP2A6,ADH1C,ADH7,CYP2C19,CYP2E1,CYP2C8,ADH5,CYP2D6
    Glutathione metabolism GSTAL,MGST1.1,GGT6,GPX4A,GPX3,RRM2B,RRM1,GSTM6,GSS,PGD
    Metabolism of water-soluble vitamins and cofactors CTRB1,ELA2,GPHN,PDZD11,CBLC-1,MOCOS,SLC5A6A,TCN1,SLC25A16,SLC19A2

    Protein Function

    GSTO2 has several biochemical functions, for example, glutathione dehydrogenase (ascorbate) activity,glutathione transferase activity,methylarsonate reductase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GSTO2 itself. We selected most functions GSTO2 had, and list some proteins which have the same functions with GSTO2. You can find most of the proteins on our site.

    Function Related Protein
    oxidoreductase activity AKR1C6,CYP4V7,CYP3A25,AOX3,CYP21A1,CYP46A1.4,RDH10A,CYP1A2,P4HA1B,SCCPDHB
    glutathione transferase activity GSTM1,GSTM,GSTA,GSTZ1,GSTA5,MGST3,GSTT4,LTC4S,GSTP1,GSTA1
    glutathione dehydrogenase (ascorbate) activity GSTO1
    methylarsonate reductase activity GSTO1
    protein binding GPATCH4,SKA3,IL7,NKD2,AP2S1,GBP5,CCDC135,POT1A,INADL,YY1A

    Interacting Protein

    GSTO2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GSTO2 here. Most of them are supplied by our site. Hope this information will be useful for your research of GSTO2.

    TFAP2A;MUM1

    Resources

    References

    • Glisic, B; Mihaljevic, I; et al. Characterization of glutathione-S-transferases in zebrafish (Danio rerio). AQUATIC TOXICOLOGY 158:50-62(2015).
    • Azizian-Farsani, F; Rafiei, G; et al. Impact of Sodium Arsenite on Chromosomal Aberrations With Respect to Polymorphisms of Detoxification and DNA Repair Genes. INTERNATIONAL JOURNAL OF TOXICOLOGY 33:518-522(2014).

    Ask a Question for All GSTO2 Products

    Required fields are marked with *

    My Review for All GSTO2 Products

    Required fields are marked with *