GRIA4
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Official Full Name
Gria4 glutamate receptor, ionotropic, AMPA4 (alpha 4) -
Synonyms
GRIA4;glutamate receptor, ionotropic, AMPA4 (alpha 4);glutamate receptor 4;spike wave 1;glutamate receptor channel alpha 4;AMPA-selective glutamate receptor 4;glutamate receptor ionotropic, AMPA 4;GluA4;Glur4;spkw1;GluR-D;Glur-4;Gluralpha4
Recombinant Proteins
- Human
- Chicken
- Mammalian Cell
- E.coli
- HEK293
- E. coli
- Wheat Germ
- In Vitro Cell Free System
- His
- His&Fc&Avi
- GST
- His&SUMO
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| GRIA4-216H | Recombinant Human GRIA4 | Mammalian Cell | Human | His |
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| GRIA4-3797C | Recombinant Chicken GRIA4 | Mammalian Cell | Chicken | His |
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| GRIA4-6767C | Recombinant Chicken GRIA4 | Mammalian Cell | Chicken | His |
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| GRIA4-2770H | Recombinant Human GRIA4 protein(731-800 aa), C-His-tagged | E.coli | Human | His | 731-800 aa |
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| GRIA4-3076H | Recombinant Human GRIA4 Protein, His (Fc)-Avi-tagged | HEK293 | Human | His&Fc&Avi |
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| GRIA4-3076H-B | Recombinant Human GRIA4 Protein Pre-coupled Magnetic Beads | HEK293 | Human |
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| GRIA4-3213H | Recombinant Human GRIA4 protein, His-tagged | E. coli | Human | His | Leu311-Val390 |
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| GRIA4-3214H | Recombinant Human GRIA4 protein, His-tagged | E.coli | Human | His | Arg385~Pro542 |
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| GRIA4-5333H | Recombinant Human GRIA4 Protein, GST-tagged | Wheat Germ | Human | GST |
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| GRIA4-5624HF | Recombinant Full Length Human GRIA4 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 433 amino acids |
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| GRIA4-954H | Recombinant Human GRIA4 Protein, His&SUMO-tagged | E.coli | Human | His&SUMO | Arg385-Pro542 |
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Involved Pathway
GRIA4 involved in several pathways and played different roles in them. We selected most pathways GRIA4 participated on our site, such as cAMP signaling pathway,Neuroactive ligand-receptor interaction,Circadian entrainment, which may be useful for your reference. Also, other proteins which involved in the same pathway with GRIA4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Retrograde endocannabinoid signaling | PLCB4,MAPK3,GABRB1,ABHD6,PLCB1,GNAO1,GNGT1,MAPK11,GABRA3,ITPR3 |
| Circadian entrainment | PRKG2,NOS1AP,GNG10,PRKG1,CAMK2D,CALM2,GRIA2,ADCYAP1R1,CACNA1H,GNB1 |
| Nicotine addiction | GABRR3,GABRA2,GABRG1,GABRG3,GABRB3,GABRE,GRIN2D,GABRA1,SLC17A7,GABRA6 |
| cAMP signaling pathway | FXYD1,CNGA1,HTR1E,ACOX3,HCAR3,HTR1B,MAPK3,AKT2,CALM3,PTGER2 |
| Glutamatergic synapse | SLC17A7,GRIN1,TRPC1,GRIN2C,PLA2G4C,GNG8,GNB4,GNGT2,PPP3R1,SLC1A3 |
| Neuroactive ligand-receptor interaction | MTNR1B,TAAR14E,NTSR2,PTH1RB,GABRA2,F2R,TAAR14G,CHRM5A,CALCR,GRIK5 |
| Dopaminergic synapse | CALML5,PPP2R1B,GSK3B,CALM3,SCN1A,GNG2,PPP2R5C,GNG12,PPP2R5E,CLOCK |
Protein Function
GRIA4 has several biochemical functions, for example, AMPA glutamate receptor activity,extracellular-glutamate-gated ion channel activity,ionotropic glutamate receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GRIA4 itself. We selected most functions GRIA4 had, and list some proteins which have the same functions with GRIA4. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| extracellular-glutamate-gated ion channel activity | GRIN2B,GRIA3A,GRIK4,KBP,GRIN2A,GRIA1A,GRIK5,GRIN3A,GRIA1,GRIN3B |
| ionotropic glutamate receptor activity | GRIN2A,KBP,GRIN1B,GRIN2BB,GRIA3B,GRID1,GRIA1B,GRIA4B,GRIA2A,GRIN3B |
| AMPA glutamate receptor activity | GRIA4A,GRIA2A,GRIA3A,GRIA2B,GRIA1B,GRIA1,GRIA3B,GRIA3,GRIA1A,GRIA2 |
Interacting Protein
GRIA4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GRIA4 here. Most of them are supplied by our site. Hope this information will be useful for your research of GRIA4.
PTBP3;PRKACA;CAMK2A
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References
- Panzer, JA; Gleichman, AJ; et al. Glutamatergic autoencephalitides: an emerging field. JOURNAL OF NEURAL TRANSMISSION 121:957-968(2014).
- Trippe, J; Steinke, K; et al. Autoantibodies to Glutamate Receptor Antigens in Multiple Sclerosis and Rasmussen's Encephalitis. NEUROIMMUNOMODULATION 21:189-194(2014).
