GPR37L1
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Official Full Name
G protein-coupled receptor 37 like 1 -
Overview
Endothelin B receptor-like protein 2 is a protein that in humans is encoded by the GPR37L1 gene. -
Synonyms
GPR37L1;G protein-coupled receptor 37 like 1;endothelin B receptor-like protein 2;ETBR LP 2;G-protein coupled receptor 37 like 1;G-protein coupled receptor 37-like 1;endothelin type b receptor-like protein 2;ETBR-LP-2;ET(B)R-LP-2
Recombinant Proteins
- Rhesus macaque
- Human
- Rat
- Bovine
- Mus musculus
- Mammalian Cells
- HEK293
- Wheat Germ
- In Vitro Cell Free System
- E.coli
- His
- Non
- Avi
- Fc
- GST
Involved Pathway
GPR37L1 involved in several pathways and played different roles in them. We selected most pathways GPR37L1 participated on our site, such as Class A/1 (Rhodopsin-like receptors),GPCR ligand binding,GPCRs, Class A Rhodopsin-like, which may be useful for your reference. Also, other proteins which involved in the same pathway with GPR37L1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| GPCRs, Class A Rhodopsin-like | DRD3,SSTR1,GPR27,FPR-RS3,PTGDR2,OR3A4P,OPN1MW,GPR171,NMUR1,CCBP2 |
| Signaling by GPCR | CCBP2,GPR65,ARHGEF25,ANXA1A,RGS21,GPR37B,CD97,PENKA,OXGR1A.2,INSL3 |
| GPCR ligand binding | OPN4,EMR2,CCRL2,CXCL13,TAS2R3,ADORA2B,TAS2R13,PMCH,LTB4R,ADCYAP1R1 |
| Signal Transduction | FSTL3,NMS,ARHGAP1,RXFP2B,CRABP2A,DNER,NPSR1,GHRB,ARHGAP10,ABI1A |
| Peptide ligand-binding receptors | RLN2,CCL35.1,SSTR5,NMS,RLN3A,PROK2,NMBA,KEL,HCRT,AMCF-II |
| Class A/1 (Rhodopsin-like receptors) | INSL3,GPR55A,DRD5,GRP,PPY,CHRM2,OXTRL,CCL19A.2,OPN1LW,SSTR3 |
Protein Function
GPR37L1 has several biochemical functions, for example, G-protein coupled peptide receptor activity,peptide binding,prosaposin receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GPR37L1 itself. We selected most functions GPR37L1 had, and list some proteins which have the same functions with GPR37L1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | SRSF2,C22orf39,SAP18,NTF4,DEDD,MNAT1,CCR5,WASF2,TTR,FCGR2A |
| G-protein coupled peptide receptor activity | NPR1,CYSLTR2,CYSLTR1,FSHR,MCHR2,GRPR,LHCGR,LTB4R2,RXFP3.2B,RXFP4 |
| prosaposin receptor activity | GPR37 |
| peptide binding | ERAP1,ERAP2,ANPEP,GNRHR,PCSK5,RPS6KB2,FNTB,GPR37,RNPEP,CLTB |
Interacting Protein
GPR37L1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GPR37L1 here. Most of them are supplied by our site. Hope this information will be useful for your research of GPR37L1.
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References
- Meyer, RC; Giddens, MM; et al. The protective role of prosaposin and its receptors in the nervous system. BRAIN RESEARCH 1585:1-12(2014).
- Marazziti, D; Di Pietro, C; et al. Precocious cerebellum development and improved motor functions in mice lacking the astrocyte cilium-, patched 1-associated Gpr37l1 receptor. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 110:16486-16491(2013).
