GNGT2

  • Official Full Name

    guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2

  • Overview

    Phototransduction in rod and cone photoreceptors is regulated by groups of signaling proteins. The encoded protein is thought to play a crucial role in cone phototransduction. It belongs to the G protein gamma family and localized specifically in cones. Several transcript variants encoding the same protein have been found for this gene.

  • Synonyms

    GNGT2;guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2;guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2;GNG9;G GAMMA 8;G gamma 9;G GAMMA C;G protein cone gamma 8 subunit;gamma T2 subunit;GNG8;GNGT8;guanine nucleotide binding protein (G protein), gamma transducing;Guanine nucleotide binding protein G;guanine nucleotide binding protein gamma 9;guanine nucleotide binding protein gamma transducing activity;IG;Ogamma T2 subunit precursor;SG;G-gamma-9;g gamma-C;gamma-T2 subunit;OTTHUMP00000220018;OTTHUMP00000220019;OTTHUMP00000220020;OTTHUMP00000220021;OTTHUMP00000220022;guanine nucleotide bindin;G-GAMMA-8;G-GAMMA-C

Recombinant Proteins

  • Human
  • Rhesus macaque
  • Chicken
  • Mouse
  • E.coli
  • Mammalian Cells
  • HEK293
  • Wheat Germ
  • In Vitro Cell Free System
  • GST
  • His
  • Non
  • Myc&DDK
  • His&Fc&Avi
Cat.# Product name Source (Host) Species Tag Protein Length Price
GNGT2-13367H Recombinant Human GNGT2, GST-tagged E.coli Human GST 1-69a.a.
GNGT2-1908R Recombinant Rhesus monkey GNGT2 Protein, His-tagged Mammalian Cells Rhesus macaque His
GNGT2-5602C Recombinant Chicken GNGT2 Mammalian Cells Chicken His
GNGT2-5849HCL Recombinant Human GNGT2 293 Cell Lysate HEK293 Human Non
Gngt2-1040M Recombinant Mouse Gngt2 Protein, MYC/DDK-tagged HEK293 Mouse Myc&DDK
GNGT2-1503H Recombinant Human GNGT2 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293 Human Myc&DDK
GNGT2-1728R Recombinant Rhesus Macaque GNGT2 Protein, His (Fc)-Avi-tagged HEK293 Rhesus macaque His&Fc&Avi
GNGT2-1728R-B Recombinant Rhesus Macaque GNGT2 Protein Pre-coupled Magnetic Beads HEK293 Rhesus macaque
GNGT2-5077H Recombinant Human GNGT2 Protein, GST-tagged Wheat Germ Human GST
GNGT2-5394HF Recombinant Full Length Human GNGT2 Protein, GST-tagged In Vitro Cell Free System Human GST Full L. 69 amino acids

    Involved Pathway

    GNGT2 involved in several pathways and played different roles in them. We selected most pathways GNGT2 participated on our site, such as Ras signaling pathway,Chemokine signaling pathway,PIK-Akt signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with GNGT2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Serotonergic synapse KCNN2,APP,PLCB4,HTR2B,GNG3,PLCB1,HTR2A,GNG13,CYP2C54,ITPR3
    Alcoholism H2AFB3,HIST2H2AC,NTRK2,GNAI1,GNAI2,MAPK1,GM14483,CREB3L2,H2AFY2,HDAC10
    Circadian entrainment PRKACA,RYR3,CACNA1G,CALML3,GNAI1,PER3,PLCB1,Adcy4,GNG7,ITPR3
    Pathways in cancer DAPK1,PIK3CD,WNT2B,RALGDS,RUNX1T1,EGLN2,FGF21,BDKRB2,WNT10B,TRP53
    PIK-Akt signaling pathway CCND3,KIT,INS1,PDGFA,HSP90B1,FGFR1,PPP2CB,G6PC3,ITGB6,OSM
    Chemokine signaling pathway SRC,CCL5,CDC42,NFKBIA,PIK3R3,GM2506,Ccl27a,CCL4L1,CCL15,LOC100033925
    Glutamatergic synapse GNB1,ITPR3,GRIK2,HOMER2,GRM6,TRPC1,GRIN2C,MAPK1,GRIN2D,PRKCB
    Ras signaling pathway ELK1,IGF1,ABL2,SHC1,PLA2G4C,FGFR4,LOC608458,RASA3,PRKCG,FGF4
    Retrograde endocannabinoid signaling GABRB3,NAPEPLD,GABRR2,GABRQ,GABRG1,GABRB2,GABRR3,GNG3,GNB1,GNG2

    Protein Function

    GNGT2 has several biochemical functions, for example, GTPase activity,signal transducer activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GNGT2 itself. We selected most functions GNGT2 had, and list some proteins which have the same functions with GNGT2. You can find most of the proteins on our site.

    Function Related Protein
    signal transducer activity TAAR12F,OLFR481,GNRHR3,OLFR150,NPFFR1L1,GNAI2A,PLCD1B,PTK2,STAT6,RHOC
    GTPase activity DNM1B,CDC42,EIF2S3,RAB11BA,TUBA3D,MX1,DNM1L,RHOQ,RAB7A,RND1

    Interacting Protein

    GNGT2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GNGT2 here. Most of them are supplied by our site. Hope this information will be useful for your research of GNGT2.

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