GNG4
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Official Full Name
guanine nucleotide binding protein (G protein), gamma 4 -
Overview
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 is a protein that in humans is encoded by the GNG4 gene. -
Synonyms
GNG4;guanine nucleotide binding protein (G protein), gamma 4;guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4;GNGT4;Guanine nucleotide-binding protein G(I)/G(S)/G(O) gamma-4 subunit;OTTHUMP00000038436;OTTHUMP00000038437;guanine nucleotide binding protein 4
Recombinant Proteins
- Human
- Mouse
- E.coli
- Mammalian Cells
- HEK293
- Wheat Germ
- In Vitro Cell Free System
- GST
- His
- DDK
- Myc
- Avi
- Fc
Involved Pathway
GNG4 involved in several pathways and played different roles in them. We selected most pathways GNG4 participated on our site, such as Ras signaling pathway,Chemokine signaling pathway,PIK-Akt signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with GNG4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Serotonergic synapse | CYP2D10,PLCB1,PRKCB,HTR2A,ARAF,HTR3C,PLCB4,MAPK1,GABRB3,SLC18A1 |
| Dopaminergic synapse | ITPR3,GNAI3,GNB1,CAMK2G,PLCB1,AKT1,PLCB2,GRIN2B,GNG3,PPP2R5A |
| GABAergic synapse | GNB1,GNG10,PRKCG,GABRA1,NSF,GNAO1,SLC12A5,GPHN,SLC6A13,PRKCB |
| Cholinergic synapse | FOS,PIK3CG,JAK2,GNG13,GNAI1,HRAS,KCNJ4,PIK3R1,GNAQ,CREB3L4 |
| Retrograde endocannabinoid signaling | PTGS2,GABRP,GNAI1,ITPR3,ABHD6,MAPK13,GNGT1,GABRG2,GNG10,GABRB1 |
| Circadian entrainment | GRIN2B,MAPK1,GNAI1,PER3,CAMK2A,KCNJ3,KCNJ6,ADCYAP1R1,AKR1C1,PRKACA |
| Pathways in cancer | FZD2,WNT1,WNT11,TRAF5,LAMA3,PRKACG,TCF7,LPAR5,EGLN3,ITGA3 |
| Glutamatergic synapse | GNG3,GNB2,GNG2,GRM4,PPP3CA,GNG5,GNG12,HOMER3,GLS2,GNAO1 |
| PIK-Akt signaling pathway | CCND3,FGF8,ITGB1,FGF17,LAMA3,MTOR,TRP53,PCK2,GNG2,LPAR3 |
Protein Function
GNG4 has several biochemical functions, for example, protein binding,signal transducer activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GNG4 itself. We selected most functions GNG4 had, and list some proteins which have the same functions with GNG4. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | SF3A1,RPS25,PINX1,MAPK8IP3,FARS2,GRIK5,MTMR9,CENPA,TACR1,CHMP4A |
| signal transducer activity | TRHRB,ASZ1,OLFR186,PRLH2R,GAB1,OLFCG3,FPR3,OLFR493,ATP2C1,TAAR12A |
Interacting Protein
GNG4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GNG4 here. Most of them are supplied by our site. Hope this information will be useful for your research of GNG4.
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References
- Padigel, UM; Stein, L; et al. Signaling through G alpha i2 protein is required for recruitment of neutrophils for antibody-mediated elimination of larval Strongyloides stercoralis in mice. JOURNAL OF LEUKOCYTE BIOLOGY 81:1120-1126(2007).
- Fabbri, E; Selva, C; et al. Identification and properties of a Gs protein in catfish liver membranes. GENERAL AND COMPARATIVE ENDOCRINOLOGY 125:340-348(2002).
