GNAI2

  • Official Full Name

    guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
  • Overview

    Guanine nucleotide-binding protein G(i), alpha-2 subunit is a protein that in humans is encoded by the GNAI2 gene.
  • Synonyms

    Giα-2-Subunit;GNAI2;Guanine nucleotide-binding protein G(i), alpha-2 subunit;Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2;GIP;GNAI2B;H_LUCA15.1;H_LUCA16.1;guanine nucleotide-binding protein G(i) subunit alpha-2;OTTHUMP00000211065;OTTHUMP00000211066;OTTHUMP00000211067;OTTHUMP00000211070;adenylate cyclase-inhibiting G alpha protein;GTP-binding regulatory protein Gi alpha-2 chain

Recombinant Proteins

  • Human
  • Rhesus macaque
  • Rat
  • Cynomolgus
  • Chicken
  • Mouse
  • E.coli
  • Mammalian Cells
  • HEK293
  • Wheat Germ
  • In Vitro Cell Free System
  • Insect Cells
  • GST
  • His
  • Flag
  • Non
  • Avi
  • Fc
  • DDK
  • Myc
Cat.# Product name Source (Host) Species Tag Protein Length Price
GNAI2-3766H Recombinant Human GNAI2 protein, GST-tagged E.coli Human GST 1-355 aa
GNAI2-190H Active Recombinant Human GNAI2 protein, GST-tagged E.coli Human GST 2-end
GNAI2-1891R Recombinant Rhesus monkey GNAI2 Protein, His-tagged Mammalian Cells Rhesus macaque His
GNAI2-2594R Recombinant Rat GNAI2 Protein Mammalian Cells Rat His
GNAI2-28964TH Recombinant Human GNAI2, His-tagged E.coli Human His Full L. 3-366 a.a.
GNAI2-31364TH Recombinant Human FPR1 Protein Human Flag&His Full L.
GNAI2-31549TH Recombinant Human Human ADRB2 Human Flag&His Full L.
GNAI2-31551TH Recombinant Human Human Human Human GNB1 Human Flag&His Full L.
GNAI2-555C Recombinant Cynomolgus GNAI2 Protein, His-tagged Mammalian Cells Cynomolgus His
GNAI2-6953C Recombinant Chicken GNAI2 Mammalian Cells Chicken His
GNAI2-7015M Recombinant Mouse GNAI2 Protein Mammalian Cells Mouse His
GNAI2-7152H Recombinant Human Guanine Nucleotide Binding Protein (G Protein), Alpha Inhibiting Activity Polypeptide 2, His-tagged E.coli Human His 1-355aa
GNAI2-5870HCL Recombinant Human GNAI2 293 Cell Lysate HEK293 Human Non
Gnai2-1229M Recombinant Mouse Gnai2 protein, His-tagged E.coli Mouse His 2-355aa
GNAI2-1711R Recombinant Rhesus Macaque GNAI2 Protein, His (Fc)-Avi-tagged HEK293 Rhesus macaque Avi&Fc&His
GNAI2-1711R-B Recombinant Rhesus Macaque GNAI2 Protein Pre-coupled Magnetic Beads HEK293 Rhesus macaque
GNAI2-2249R Recombinant Rat GNAI2 Protein, His (Fc)-Avi-tagged HEK293 Rat Avi&Fc&His
GNAI2-2249R-B Recombinant Rat GNAI2 Protein Pre-coupled Magnetic Beads HEK293 Rat
GNAI2-300C Recombinant Cynomolgus Monkey GNAI2 Protein, His (Fc)-Avi-tagged HEK293 Cynomolgus Avi&Fc&His
GNAI2-300C-B Recombinant Cynomolgus Monkey GNAI2 Protein Pre-coupled Magnetic Beads HEK293 Cynomolgus
Gnai2-3255M Recombinant Mouse Gnai2 Protein, Myc/DDK-tagged HEK293 Mouse DDK&Myc
GNAI2-3757M Recombinant Mouse GNAI2 Protein, His (Fc)-Avi-tagged HEK293 Mouse Avi&Fc&His
GNAI2-3757M-B Recombinant Mouse GNAI2 Protein Pre-coupled Magnetic Beads HEK293 Mouse
GNAI2-5042H Recombinant Human GNAI2 Protein, GST-tagged Wheat Germ Human GST
GNAI2-5323HF Recombinant Full Length Human GNAI2 Protein, GST-tagged In Vitro Cell Free System Human GST Full L. 339 amino acids
Gnai2-5898M Recombinant Mouse Gnai2 protein, His&Myc-tagged Insect Cells Mouse His&Myc 2-355aa
GNAI2-944HFL Recombinant Full Length Human GNAI2 Protein, C-Flag-tagged Mammalian Cells Human Flag Full L.
GNAI2-996H Recombinant Human GNAI2 Protein, His (Fc)-Avi-tagged HEK293 Human Avi&Fc&His
GNAI2-996H-B Recombinant Human GNAI2 Protein Pre-coupled Magnetic Beads HEK293 Human

    Involved Pathway

    GNAI2 involved in several pathways and played different roles in them. We selected most pathways GNAI2 participated on our site, such as Rap signaling pathway,cGMP-PKG signaling pathway,cAMP signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with GNAI2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Sphingolipid signaling pathway ROCK1,SPTLC2,SPHK1,PPP2R1B,MAP3K5,AKT1,ASAH2,PPP2CB,PPP2R5B,PPP2R5E
    Gastric acid secretion ATP4A,ACTB,CALML3,EZR,PRKCB,KCNJ16,KCNK10,CCKBR,KCNJ2,Adcy4
    Rap signaling pathway MAPK3,MAPK1,NGFR,FGFR3,FGF9,RASGRP3,SKAP1,RAPGEF1,ANGPT4,VEGFA
    Circadian entrainment KCNJ9,GNAI1,RPS6KA5,GNG3,CALML5,GNB3,PLCB4,GNG5,CACNA1H,RYR1
    Estrogen signaling pathway PIK3R2,SOS1,MAP2K2,OPRM1,AKT2,GPR30,PLCB3,SRC,CALM3,NRAS
    Chagas disease (American trypanosomiasis) TLR4,CD3D,IFNGR1,C1QC,CD247,NFKB1,TLR9,GNAS,IL1B2,TGFB3
    Gap junction GNAS,TUBA1A,PRKCA,GRM1,MAP2K2A,CSNK1DB,GNAIA,DRD1A,GNAI2B,TUBA3A
    Pertussis IL1B,Hc,C3,NLRP3,NFKB1,Il23a,Il23a; Il12b,CXCL6,IL12B,IL-8
    Alcoholism SLC18A1,SHC1,HIST1H3A,GM14477,HIST1H2BL,MAP2K1,GNG2,SLC29A1,HIST3H2BB-PS,GRIN3A

    Protein Function

    GNAI2 has several biochemical functions, for example, G-protein beta/gamma-subunit complex binding,G-protein coupled receptor binding,GTP binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GNAI2 itself. We selected most functions GNAI2 had, and list some proteins which have the same functions with GNAI2. You can find most of the proteins on our site.

    Function Related Protein
    protein binding TTC1,SASS6,LNX2B,DYRK1B,SMR3B,DDIT4L,LEF1,ELF4,FBLN1,RBMY1A1
    signal transducer activity VMN1R50,OLFCQ19,ADORA2AA,TAAR14D,MRGPRB5,CXCR4A,DRD1A,MTNR1C,VMN1R45,GNG3
    GTPase activity MXA,GNA12A,RIT2,SAR1B,HBS1L,RAB39B,GBP1,RAN,RAB36,RAB39BA
    metal ion binding ZNF557,MAP2K2,ZNF16,CSGALNACT1,DAK,FAM20B,JMJD5,CPEB1B,CAR1,REPIN1
    G-protein beta/gamma-subunit complex binding GNAS,GNA11A,GNAV1,GNAZ,GNAT1,GNAT2,GNA13,GNA13B,GNA15.1,GNA15.4
    G-protein coupled receptor binding PROK2,RSPO1,GNA14,NPB,PICK1,GNAI2B,DNAJA1,NPFFL,POMC,GPRC5B
    GTP binding DNM3A,RAB8A,RTKN,RASEF,EEF2A.2,TRIM66,HRASB,RAC1,RAB12,RAB5B

    Interacting Protein

    GNAI2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GNAI2 here. Most of them are supplied by our site. Hope this information will be useful for your research of GNAI2.

    CXCR5;MDFI;NCF2;RGS20;HSP90AB1

    Resources

    References

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