GNA14

  • Official Full Name

    guanine nucleotide binding protein (G protein), alpha 14
  • Synonyms

    GNA14;guanine nucleotide binding protein (G protein), alpha 14;guanine nucleotide-binding protein subunit alpha-14;g alpha-14;G-protein subunit alpha-14;guanine nucleotide-binding protein 14

Recombinant Proteins

  • Human
  • Zebrafish
  • Rhesus macaque
  • Mouse
  • E.coli
  • Mammalian Cells
  • HEK293
  • Wheat Germ
  • In Vitro Cell Free System
  • GST
  • His
  • Non
  • Avi
  • Fc
Cat.# Product name Source (Host) Species Tag Protein Length Price
GNA14-13344H Recombinant Human GNA14, GST-tagged E.coli Human GST 1-355a.a.
GNA14-1090Z Recombinant Zebrafish GNA14 Mammalian Cells Zebrafish His
GNA14-188H Recombinant Human GNA14 protein, GST-tagged E.coli Human GST
GNA14-1890R Recombinant Rhesus monkey GNA14 Protein, His-tagged Mammalian Cells Rhesus macaque His
GNA14-7012M Recombinant Mouse GNA14 Protein Mammalian Cells Mouse His
GNA14-721HCL Recombinant Human GNA14 cell lysate Human Non
GNA14-1710R Recombinant Rhesus Macaque GNA14 Protein, His (Fc)-Avi-tagged HEK293 Rhesus macaque Avi&Fc&His
GNA14-1710R-B Recombinant Rhesus Macaque GNA14 Protein Pre-coupled Magnetic Beads HEK293 Rhesus macaque
GNA14-3754M Recombinant Mouse GNA14 Protein, His (Fc)-Avi-tagged HEK293 Mouse Avi&Fc&His
GNA14-3754M-B Recombinant Mouse GNA14 Protein Pre-coupled Magnetic Beads HEK293 Mouse
GNA14-5026H Recombinant Human GNA14 Protein, GST-tagged Wheat Germ Human GST
GNA14-5423HF Recombinant Full Length Human GNA14 Protein, GST-tagged In Vitro Cell Free System Human GST Full L. 355 amino acids

    Involved Pathway

    GNA14 involved in several pathways and played different roles in them. We selected most pathways GNA14 participated on our site, such as Calcium signaling pathway,Chagas disease (American trypanosomiasis),Amoebiasis, which may be useful for your reference. Also, other proteins which involved in the same pathway with GNA14 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Calcium signaling pathway CAMK2D1,PRKCG,EGFRA,PLCB1,PRKACG,P2RX4A,ADCY1A,PPP3CB,CACNA1H,PPIF
    Amoebiasis RAB5B,LAMA1,CXCL8,COL1A1,CSF2,LAMA5,IL-8,C8G,LAMB4,COL4A1
    Chagas disease (American trypanosomiasis) IRAK1,TICAM1,TLR4,CD3G,FAS,MAPK9,IL6,PPP2R2B,PIK3CG,CD3D

    Protein Function

    GNA14 has several biochemical functions, for example, G-protein beta/gamma-subunit complex binding,G-protein coupled receptor binding,GTP binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GNA14 itself. We selected most functions GNA14 had, and list some proteins which have the same functions with GNA14. You can find most of the proteins on our site.

    Function Related Protein
    GTPase activity RAB36,MX1,RHOA,RAB11B,TUBB5,RIT2,TUBB2,RND3,RAB2A,RAP1GAP
    signal transducer activity CD24,DRD4B,OLFR147,TAAR14I,MAVS,MRGPRB1,GNAI2,STAT6,GPR183B,TRAF2
    G-protein beta/gamma-subunit complex binding GNAT1,CETN1,GNA13A,GNAZ,GNA15,GNA11B,GNAS,GNAV1,PIK3R5,CETN4
    G-protein coupled receptor binding HAND2,HSPA8,UTS2D,GNA11B,DNAJA1,GNAT2,RSPO3,PROK2,GNAI2A,GNAT3
    metal ion binding AOC1,NPAS2,S100S,NAIP7,CLCNKA,SNAI1A,PLRDGB,CALUB,DTD1,MPPED2
    protein binding STEAP3,HJURP,UBC,SGCA,CEACAM21,TIMELESS,FYN,HIST1H1C,ACLY,MORN3
    GTP binding GMPPB,AK3,RAB17,URGCP,ERCC3,GNA13B,RAB3C,FPGT,RHOV,RHOBTB2A

    Interacting Protein

    GNA14 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GNA14 here. Most of them are supplied by our site. Hope this information will be useful for your research of GNA14.

    DNAL4;JMJD6;SNW1

    Resources

    References

    • Giusti, L; Taddei, S; et al. Alkylation of sulfhydryl groups on G alpha(s/olf) subunits by N-ethylmaleimide: regulation by guanine nucleotides. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES 1613:7-14(2003).
    • Avissar, S; Nechamkin, Y; et al. Dynamics of ECT normalization of low G protein function and immunoreactivity in mononuclear leukocytes of patients with major depression. AMERICAN JOURNAL OF PSYCHIATRY 155:666-671(1998).

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