GNA14
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Official Full Name
guanine nucleotide binding protein (G protein), alpha 14 -
Synonyms
GNA14;guanine nucleotide binding protein (G protein), alpha 14;guanine nucleotide-binding protein subunit alpha-14;g alpha-14;G-protein subunit alpha-14;guanine nucleotide-binding protein 14
Recombinant Proteins
- Human
- Zebrafish
- Rhesus macaque
- Mouse
- E.coli
- Mammalian Cells
- HEK293
- Wheat Germ
- In Vitro Cell Free System
- GST
- His
- Non
- Avi
- Fc
Involved Pathway
GNA14 involved in several pathways and played different roles in them. We selected most pathways GNA14 participated on our site, such as Calcium signaling pathway,Chagas disease (American trypanosomiasis),Amoebiasis, which may be useful for your reference. Also, other proteins which involved in the same pathway with GNA14 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Calcium signaling pathway | CAMK2D1,PRKCG,EGFRA,PLCB1,PRKACG,P2RX4A,ADCY1A,PPP3CB,CACNA1H,PPIF |
| Amoebiasis | RAB5B,LAMA1,CXCL8,COL1A1,CSF2,LAMA5,IL-8,C8G,LAMB4,COL4A1 |
| Chagas disease (American trypanosomiasis) | IRAK1,TICAM1,TLR4,CD3G,FAS,MAPK9,IL6,PPP2R2B,PIK3CG,CD3D |
Protein Function
GNA14 has several biochemical functions, for example, G-protein beta/gamma-subunit complex binding,G-protein coupled receptor binding,GTP binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GNA14 itself. We selected most functions GNA14 had, and list some proteins which have the same functions with GNA14. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| GTPase activity | RAB36,MX1,RHOA,RAB11B,TUBB5,RIT2,TUBB2,RND3,RAB2A,RAP1GAP |
| signal transducer activity | CD24,DRD4B,OLFR147,TAAR14I,MAVS,MRGPRB1,GNAI2,STAT6,GPR183B,TRAF2 |
| G-protein beta/gamma-subunit complex binding | GNAT1,CETN1,GNA13A,GNAZ,GNA15,GNA11B,GNAS,GNAV1,PIK3R5,CETN4 |
| G-protein coupled receptor binding | HAND2,HSPA8,UTS2D,GNA11B,DNAJA1,GNAT2,RSPO3,PROK2,GNAI2A,GNAT3 |
| metal ion binding | AOC1,NPAS2,S100S,NAIP7,CLCNKA,SNAI1A,PLRDGB,CALUB,DTD1,MPPED2 |
| protein binding | STEAP3,HJURP,UBC,SGCA,CEACAM21,TIMELESS,FYN,HIST1H1C,ACLY,MORN3 |
| GTP binding | GMPPB,AK3,RAB17,URGCP,ERCC3,GNA13B,RAB3C,FPGT,RHOV,RHOBTB2A |
Interacting Protein
GNA14 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GNA14 here. Most of them are supplied by our site. Hope this information will be useful for your research of GNA14.
DNAL4;JMJD6;SNW1
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References
- Giusti, L; Taddei, S; et al. Alkylation of sulfhydryl groups on G alpha(s/olf) subunits by N-ethylmaleimide: regulation by guanine nucleotides. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES 1613:7-14(2003).
- Avissar, S; Nechamkin, Y; et al. Dynamics of ECT normalization of low G protein function and immunoreactivity in mononuclear leukocytes of patients with major depression. AMERICAN JOURNAL OF PSYCHIATRY 155:666-671(1998).
