GLUD1
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Official Full Name
glutamate dehydrogenase 1 -
Overview
Glutamic acid is one of the 20-22 proteinogenic amino acids, and its codons are GAA and GAG. It is a non-essential amino acid. The carboxylate anions and salts of glutamic acid are known as glutamates. In neuroscience, glutamate is an important neurotransmitter that plays a key role in long-term potentiation and is important for learning and memory. -
Synonyms
Glutamic acid;Glu;E;glutamates;D-Glutamate;D-Glutaminsure;d-glutamicaci;GLUD1;glutamate dehydrogenase 1
Recombinant Proteins
- Human
- Rat
- Mouse
- E.coli
- Mammalian Cells
- HEK293
- Wheat Germ
- In Vitro Cell Free System
- His
- Flag
- Non
- His&Fc&Avi
- Myc&DDK
- GST
Involved Pathway
GLUD1 involved in several pathways and played different roles in them. We selected most pathways GLUD1 participated on our site, such as Arginine biosynthesis,Alanine, aspartate and glutamate metabolism,D-Glutamine and D-glutamate metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with GLUD1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Arginine biosynthesis | GLULB,NOS2B,NOS2A,GLUD1B,GPT2L,ASS1,ACY1,NOS2,GOT2A,CPS1 |
| Alanine, aspartate and glutamate metabolism | GPT2,ASL2,ALDH4A1,NAT8L,AGXTA,ABAT,GOT1,GLSA,FOLH1,AGXTB |
| Proximal tubule bicarbonate reclamation | ATP1A4,AQP1,MDH1,CA4,Car2,Car4,SLC4A4,ATP1A3,ATP1B3,SLC9A3 |
| Nitrogen metabolism | CA5B,CAR6,CA12,CAR13,Car8,GLUD1A,GLULA,CA4B,CA4,GLULB |
| D-Glutamine and D-glutamate metabolism | ybaS,GLSA,GLUD2,GLS,GLUD1B,GLS2,GLUD1A |
| Carbon metabolism | PGD,GPT,SUCLG2,PGK1,IDH3A,FH1,RGN,ENO1,ECHS1,ACSS1 |
| Metabolic pathways | POLE3,GGT1,NMNAT3,PTGES,MDH2,A4GALT,ALAS2,SDSL,ADO,GAL3ST1A |
Protein Function
GLUD1 has several biochemical functions, for example, ADP binding,ATP binding,GTP binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GLUD1 itself. We selected most functions GLUD1 had, and list some proteins which have the same functions with GLUD1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| identical protein binding | FKBP8,ACPP,B2M,CLDN17,USP2,DRD2,COIL,GRB2,PHC2,CLDN7 |
| ADP binding | PRPS1,PRKAG2,ABCG1,ME1,MYO7A,MYH10,ERN1,MYO3A,MYO6,ACTA1 |
| GTP binding | GIMAP2,ARL8A,C9orf86,ARL17B,GNL3L,RAB31,NOA1,RAB14L,IRGF1,ARL15 |
| protein binding | EXOSC10,TRIM41,ZBTB16,UGGT1,EWSR1A,TRIM23,CRY1,UBE2M,TNNI1,BMI1 |
| glutamate dehydrogenase [NAD(P)+] activity | GLUD2 |
| NAD+ binding | HADH,SIRT2,SIRT6,SIRT7,UXS1,SIRT3,SIRT5,HPGD,ALDH1A3,SIRT4 |
| ATP binding | ATP2B1A,ETNK1,IDE,KITA,DHX34,MOV10B.1,UBA1,NME2B.2,MAPKAPK5,MADD |
| leucine binding | GLUD2,UBR2,UBR1 |
| glutamate dehydrogenase (NAD+) activity | GLUD2 |
Interacting Protein
GLUD1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GLUD1 here. Most of them are supplied by our site. Hope this information will be useful for your research of GLUD1.
r162;a-kg;(-)-epigallocatechin 3-gallate;purpurin;MAP3K1;MAP3K14;TRAF6;CRP;ORM1
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