GLC8
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Official Full Name
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Overview
GLC8 is a regulatory subunit of protein phosphatase 1 (Glc7p). This protein involved in glycogen metabolism and chromosome segregation, proposed to regulate Glc7p activity via conformational alteration; ortholog of the mammalian protein phosphatase inhibitor 2. Under normal conditions, Glc8p activates Glc7p, but when Glc8p is over produced, it may also inhibit Glc7p function. Glc8p is activated upon phosphoylation by Pho85p complexed with four cyclins (Pcl6p, Pcl7p, Pcl8p, or Pcl10p). -
Synonyms
Glc8p;Regulatory subunit of protein phosphatase 1 (Glc7p);involved in glycogen metabolism and chromosome segregation;proposed to regulate Glc7p activity via conformational alteration;ortholog of the mammalian protein phosphatase inhibitor 2
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
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| GLC8-346Y | Recombinant Yeast Glc8p, His-tagged | E.coli | Yeast | His |
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| GLC8-4377Y | Recombinant Yeast Glc8p, His-tagged | Yeast | S.cerevisiae | His | 1-229 a.a. |
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Involved Pathway
GLC8 involved in several pathways and played different roles in them. We selected most pathways GLC8 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with GLC8 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
GLC8 has several biochemical functions, for example, enzyme activator activity,protein phosphatase inhibitor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GLC8 itself. We selected most functions GLC8 had, and list some proteins which have the same functions with GLC8. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein phosphatase inhibitor activity | PPP1R10,URI1,PPP1R36,PPP1R27,PHACTR3,PHACTR1,ENSA,SH3RF2,PPP1R14A,DYSFIP1 |
| enzyme activator activity | APOA5,DCP1A,ALDH1A2,CXCL1,ASAP2,PRKCE,HSPB2,CASP9,RICTOR,TAB1 |
Interacting Protein
GLC8 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GLC8 here. Most of them are supplied by our site. Hope this information will be useful for your research of GLC8.
GLC7;SSB1;PHO85;PPZ2;HSP32;BNI4
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