GJC1

  • Official Full Name

    gap junction protein, gamma 1, 45kDa
  • Overview

    This gene is a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. Alternatively spliced transcript variants encoding the same isoform have been described. [provided by RefSeq, Jul 2008]
  • Synonyms

    GJC1;gap junction protein, gamma 1, 45kDa;CX45;GJA7;gap junction gamma-1 protein;connexin 45;connexin-45;gap junction alpha-7 protein

Recombinant Proteins

  • Human
  • Rhesus macaque
  • Chicken
  • Xenopus laevis
  • Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
  • Rat
  • Dog
  • Cricetulus griseus
  • Bovine
  • Mus musculus
  • Sus scrofa (Pig)
  • Mesocricetus auratus
  • zebrafish
  • E.coli
  • Mammalian Cells
  • HEK293
  • Wheat Germ
  • His
  • Non
  • His&Fc&Avi
  • GST
Cat.# Product name Source (Host) Species Tag Protein Length Price
GJC1-13282H Recombinant Human GJC1 protein, His-tagged E.coli Human His 248-396 aa
GJC1-1861R Recombinant Rhesus monkey GJC1 Protein, His-tagged Mammalian Cells Rhesus macaque His
GJC1-7052C Recombinant Chicken GJC1 Mammalian Cells Chicken His
GJC1-294HCL Recombinant Human GJC1 lysate HEK293 Human Non
GJC1-1681R Recombinant Rhesus Macaque GJC1 Protein, His (Fc)-Avi-tagged HEK293 Rhesus macaque His&Fc&Avi
GJC1-1681R-B Recombinant Rhesus Macaque GJC1 Protein Pre-coupled Magnetic Beads HEK293 Rhesus macaque
GJC1-4923H Recombinant Human GJC1 Protein, GST-tagged Wheat Germ Human GST
RFL1022GF Recombinant Full Length Chicken Gap Junction Gamma-1 Protein(Gjc1) Protein, His-Tagged E.coli Chicken His Full L. Full Length (1-394)
RFL10290XF Recombinant Full Length Xenopus Laevis Gap Junction Gamma-1 Protein(Gjc1) Protein, His-Tagged E.coli Xenopus laevis His Full L. Full Length (1-377)
RFL11624XF Recombinant Full Length Xenopus Tropicalis Gap Junction Gamma-1 Protein(Gjc1) Protein, His-Tagged E.coli Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) His Full L. Full Length (1-377)
RFL14177RF Recombinant Full Length Rat Gap Junction Gamma-1 Protein(Gjc1) Protein, His-Tagged E.coli Rat His Full L. Full Length (1-396)
RFL17598CF Recombinant Full Length Dog Gap Junction Gamma-1 Protein(Gjc1) Protein, His-Tagged E.coli Dog His Full L. Full Length (1-396)
RFL18429CF Recombinant Full Length Cricetulus Griseus Gap Junction Gamma-1 Protein(Gjc1) Protein, His-Tagged E.coli Cricetulus griseus His Full L. Full Length (1-396)
RFL20600BF Recombinant Full Length Bovine Gap Junction Gamma-1 Protein(Gjc1) Protein, His-Tagged E.coli Bovine His Full L. Full Length (1-396)
RFL22112HF Recombinant Full Length Human Gap Junction Gamma-1 Protein(Gjc1) Protein, His-Tagged E.coli Human His Full L. Full Length (1-396)
RFL27059MF Recombinant Full Length Mouse Gap Junction Gamma-1 Protein(Gjc1) Protein, His-Tagged E.coli Mus musculus His Full L. Full Length (1-396)
RFL32772SF Recombinant Full Length Pig Gap Junction Gamma-1 Protein(Gjc1) Protein, His-Tagged E.coli Sus scrofa (Pig) His Full L. Full Length (1-396)
RFL35051MF Recombinant Full Length Mesocricetus Auratus Gap Junction Gamma-1 Protein(Gjc1) Protein, His-Tagged E.coli Mesocricetus auratus His Full L. Full Length (1-396)
RFL35362DF Recombinant Full Length Danio Rerio Gap Junction Gamma-1 Protein(Gjc1) Protein, His-Tagged E.coli zebrafish His Full L. Full Length (1-380)

    Involved Pathway

    GJC1 involved in several pathways and played different roles in them. We selected most pathways GJC1 participated on our site, such as Calcium Regulation in the Cardiac Cell,Electric Transmission Across Gap Junctions,Gap junction assembly, which may be useful for your reference. Also, other proteins which involved in the same pathway with GJC1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Gap junction assembly CX27.5,GJA8,GJD3,GJB4,GJB5,GJB2,GJB3,CX30.3,GJB7,GJA4
    Gap junction trafficking CX27.5,CX30.3,GJD3,GJB4,MYO6,GJA8,DAB2,GJB5,MYO6B,GJB2
    Transmission across Electrical Synapses PANX1,PANX1A,GJA10,PANX2,PANX1B
    Neuronal System KCNC4,SYT1A,PANX2,KCNC1,KCNA1,KCNA10,KCNC2,KCNK16,KCNMB2,PANX1B
    Calcium Regulation in the Cardiac Cell GNB5B,GJB5,CX27.5,ADRB1,RGS4,CX30.3,RGS17,RGS19,ADRB3,RGS20
    Gap junction trafficking and regulation GJB5,GJB2,MYO6A,GJB4,GJA4,DAB2,GJB3,CX27.5,CX30.3,MYO6B
    Electric Transmission Across Gap Junctions PANX1A,GJA10,PANX1B,PANX1,PANX2
    Membrane Trafficking PREB,GJB5,TMED2,CNIH3,DTNBP1B,PICALMA,SNF8,DNASE2,SNX9A,TRAPPC2

    Protein Function

    GJC1 has several biochemical functions, for example, gap junction channel activity,ion channel activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GJC1 itself. We selected most functions GJC1 had, and list some proteins which have the same functions with GJC1. You can find most of the proteins on our site.

    Function Related Protein
    ion channel activity KCNB2,FXYD6L,TRPN1,P2RX4B,CLCN4-2,TRPV2,TRPC2B,GRIN1A,TRPC2,GABRA6A
    gap junction channel activity GJB2,CX23,GJA10,GJA8,GJC2,GJD3,CX43,CX52.6,PANX2,GJA1

    Interacting Protein

    GJC1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GJC1 here. Most of them are supplied by our site. Hope this information will be useful for your research of GJC1.

    Resources

    References

    • Sohl, G; Joussen, A; et al. Expression of connexin genes in the human retina. BMC OPHTHALMOLOGY 10:-(2010).

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