GJA10
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Official Full Name
gap junction protein, alpha 10, 62kDa -
Overview
Connexins, such as GJA10, are involved in the formation of gap junctions, intercellular conduits that directly connect;the cytoplasms of contacting cells. Each gap junction channel is formed by docking of 2 hemichannels, each of which;contains 6 connexin subunits (Sohl et al., 2003 (PubMed 12881038)). -
Synonyms
GJA10;gap junction protein, alpha 10, 62kDa;gap junction alpha-10 protein;connexin 62;CX62;Gap junction alpha 10;Connexin 58;Connexin 59;Connexin-62;CX58;CX59;CXA10_HUMAN;Gap junction alpha 10 protein;Gap junction alpha 9 protein;Gap junction protein alpha 10 59kDa;Gap junction protein alpha 9 59kDa;MGC50985;OTTHUMP00000016858;RP11-63K6.6
Recombinant Proteins
- Rhesus macaque
- Mouse
- Human
- Mus musculus
- Mammalian Cells
- HEK293
- Wheat Germ
- In Vitro Cell Free System
- E.coli
- His
- His&Fc&Avi
- GST
Involved Pathway
GJA10 involved in several pathways and played different roles in them. We selected most pathways GJA10 participated on our site, such as Calcium Regulation in the Cardiac Cell,Electric Transmission Across Gap Junctions,Neuronal System, which may be useful for your reference. Also, other proteins which involved in the same pathway with GJA10 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Calcium Regulation in the Cardiac Cell | CX44.1,CHRM4,KCNJ3,ADRB1,RGS7,CCDC102A,KCNB1,CX55.5,ANXA6,RGS10 |
| Electric Transmission Across Gap Junctions | PANX1,PANX2,PANX1B,PANX1A,GJC1 |
| Transmission across Electrical Synapses | PANX1B,GJC1,PANX1A,PANX1,PANX2 |
| Neuronal System | KCNJ1,KCNK7,KCNA2,PPFIA4,PICK1,KCNH1B,KCNH8,KCNH5A,STXBP1A,CPLX1 |
Protein Function
GJA10 has several biochemical functions, for example, gap junction channel activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GJA10 itself. We selected most functions GJA10 had, and list some proteins which have the same functions with GJA10. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| gap junction channel activity | GJD3,GJA8,CX30.3,CX52.6,GJC2,CX43,GJB2,GJA1,GJC1,PANX2 |
Interacting Protein
GJA10 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GJA10 here. Most of them are supplied by our site. Hope this information will be useful for your research of GJA10.
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