GHRL
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Official Full Name
Ghrelin/Obestatin Prepropeptide -
Overview
Ghrelin is a hormone produced mainly by P/D1 cells lining the fundus of the human stomach and epsilon cells of the pancreas that stimulates hunger. Ghrelin levels increase before meals and decrease after meals. It is considered the counterpart of the hormone leptin, produced by adipose tissue, which induces satiation when present at higher levels. In some bariatric procedures, the level of ghrelin is reduced in patients, thus causing satiation before it would normally occur. -
Synonyms
Ghrelin/obestatin prepropeptide;obestatin;ghrelin,growth hormone secretagogue receptor ligand;Growth hormone-releasing peptide;appetite-regulating hormone;Motilin related peptide;ghrelin/obestatin preprohormone;Growth hormone secretagogue;proteinM46;ghrelin;MTLRP;OTTHUMP00000207791;OTTHUMP00000207792;OTTHUMP00000207790;OTTHUMP00000207793;OTTHUMP00000207794;OTTHUMP00000207795;OTTHUMP00000207796;OTTHUMP00000207797;OTTHUMP00000207798;OTTHUMP00000226986;GHRL
Recombinant Proteins
- Chicken
- Human
- Rhesus macaque
- Rat
- Zebrafish
- Mouse
- Dog
- Cat
- Mammalian Cells
- E.coli
- Human
- HEK293
- Wheat Germ
- In Vitro Cell Free System
- His
- Non
- His&GST
- His&Fc&Avi
- C-His&Flag
- Myc&DDK
- GST
- N-His-KSI
Involved Pathway
GHRL involved in several pathways and played different roles in them. We selected most pathways GHRL participated on our site, such as cAMP signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with GHRL were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| cAMP signaling pathway | GRIA1,RRAS2,ATP1A2,PDE4B,PIK3CG,GABBR2,HTR1A,RAF1,PIK3CB,ATP1B4 |
Protein Function
GHRL has several biochemical functions, for example, G-protein coupled receptor binding,ghrelin receptor binding,growth hormone-releasing hormone activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GHRL itself. We selected most functions GHRL had, and list some proteins which have the same functions with GHRL. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein tyrosine kinase activator activity | AFAP1L2,PAK2,ERCC6,ABI1B,ERBB3,ABI1,CD24,NRG1,ABI1A,GAS6 |
| G-protein coupled receptor binding | RSPO3,PSAPL1,PROK2,GPRC5B,HSPA1B,UTS2D,ITGB4,NPFFL,SFTPB,GNA14 |
| protein binding | PMM2,ASB3,HIF1AN,FAM20A,HCST,PQBP1,SNX9,CCNB2,SMURF2,KCTD13 |
| growth hormone-releasing hormone activity | GHRH |
Interacting Protein
GHRL has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GHRL here. Most of them are supplied by our site. Hope this information will be useful for your research of GHRL.
UBQLN1;UBQLN1
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