GFER
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Official Full Name
growth factor, augmenter of liver regeneration -
Overview
The hepatotrophic factor designated augmenter of liver regeneration (ALR) is thought to be one of the factors responsible for the extraordinary regenerative capacity of mammalian liver. It has also been called hepatic regenerative stimulation substance (HSS). The gene resides on chromosome 16 in the interval containing the locus for polycystic kidney disease (PKD1). The putative gene product is 42% similar to the scERV1 protein of yeast. The yeast scERV1 gene had been found to be essential for oxidative phosphorylation, the maintenance of mitochondrial genomes, and the cell division cycle. The human gene is both the structural and functional homolog of the yeast scERV1 gene. [provided by RefSeq, Jul 2008] -
Synonyms
GFER;growth factor, augmenter of liver regeneration;ALR;HPO;HSS;ERV1;HPO1;HPO2;HERV1;FAD-linked sulfhydryl oxidase ALR;ERV1 homolog;hepatopoietin protein;erv1-like growth factor;hepatic regenerative stimulation substance
Recombinant Proteins
- Rat
- Human
- Zebrafish
- Mouse
- E.coli
- HEK293
- Mammalian Cells
- Wheat Germ
- In Vitro Cell Free System
- His&SUMO
- His
- Non
- Myc&DDK
- His&T7
- His&Fc&Avi
- GST
Involved Pathway
GFER involved in several pathways and played different roles in them. We selected most pathways GFER participated on our site, such as Metabolism of proteins,Mitochondrial protein import, which may be useful for your reference. Also, other proteins which involved in the same pathway with GFER were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Mitochondrial protein import | TIMM13,DNAJC19,CHCHD4,TOMM70A,MTX1,PAM16,SAMM50,HSCB,MTX2,SLC25A13 |
| Metabolism of proteins | TMED10,ODAM,CPA3,IGFBP5,IGFBP6A,SAMM50,FBXW9,FURINA,NSMCE1,UBA2 |
Protein Function
GFER has several biochemical functions, for example, flavin adenine dinucleotide binding,growth factor activity,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GFER itself. We selected most functions GFER had, and list some proteins which have the same functions with GFER. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| flavin adenine dinucleotide binding | KDM1A,AIFM2,DLD,ACADS,GSR,FMO2,XDH,MAOB,NDOR1,ACOX2 |
| thiol oxidase activity | TMX3 |
| growth factor activity | AGT,GSDF,VEGFB,IGF3,NTF3,FGF6B,TGFB2,PSPN,AMBN,MSTNB |
| protein binding | RND2,LDB1,CT45A3,VPS33B,GTF2E2,CTAG2,DPPA4,POLL,TNK2,NR1D1 |
| protein disulfide oxidoreductase activity | ERO1L,GRXCR1,PTGESL,CHCHD4,DNAJC10,ENOX2,TXN2,GLRX2,GLRX3,GRX2 |
Interacting Protein
GFER has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GFER here. Most of them are supplied by our site. Hope this information will be useful for your research of GFER.
COPS2;GPS1;COPS5;COPS8;PLEKHF2
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