GBP1

  • Official Full Name

    guanylate binding protein 1, interferon-inducible

  • Overview

    Guanylate binding protein expression is induced by interferon. Guanylate binding proteins are characterized by their ability to specifically bind guanine nucleotides (GMP, GDP, and GTP) and are distinguished from the GTP-binding proteins by the presence of 2 binding motifs rather than 3.

  • Synonyms

    GBP1;guanylate binding protein 1, interferon-inducible;guanylate binding protein 1, interferon inducible, 67kDa;interferon-induced guanylate-binding protein 1;GBP-1;huGBP-1;GTP-binding protein 1;guanine nucleotide-binding protein 1;guanylate bindi

Recombinant Proteins

  • Human
  • Zebrafish
  • Pig
  • E.coli
  • Wheat Germ
  • Mammalian Cells
  • HEK293
  • Human Cells
  • In Vitro Cell Free System
  • GST
  • Non
  • His
  • DDK
  • Myc
  • Flag
  • Avi
  • Fc
Cat.# Product name Source (Host) Species Tag Protein Length Price
GBP1-13180H Recombinant Human GBP1, GST-tagged E.coli Human GST 242-592a.a.
GBP1-28991TH Recombinant Human GBP1 Wheat Germ Human Non 592 amino acids
GBP1-492Z Recombinant Zebrafish GBP1 Mammalian Cells Zebrafish His
GBP1-53H Recombinant Human GBP1 protein, His-tagged E.coli Human His 607aa
GBP1-6940H Recombinant Human GBP1 protein(Met1-Cys589), His-tagged HEK293 Human His 1-589 a.a.
GBP1-1686HCL Recombinant Human GBP1 cell lysate Human Cells Human Non
GBP1-13181H Recombinant Human GBP1 protein, His-tagged E.coli Human His 242-592 aa
GBP1-1324H Recombinant Human GBP1 Protein, MYC/DDK-tagged HEK293 Human DDK&Myc
GBP1-182HF Recombinant Full Length Human GBP1 Protein In Vitro Cell Free System Human Full L. 592 amino acids
GBP1-2023HFL Recombinant Full Length Human GBP1 Protein, C-Flag-tagged Mammalian Cells Human Flag Full L.
GBP1-4776H Recombinant Human GBP1 Protein, GST-tagged Wheat Germ Human GST
GBP1-5522HF Recombinant Full Length Human GBP1 Protein, GST-tagged In Vitro Cell Free System Human GST Full L. 592 amino acids
GBP1-5526H Recombinant Human GBP1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293 Human DDK&Myc
GBP1-945P Recombinant Pig GBP1 Protein, His-tagged E.coli Pig His Lys35-Lys275
GBP1-968H Recombinant Human GBP1 Protein, His (Fc)-Avi-tagged HEK293 Human Avi&Fc&His
GBP1-968H-B Recombinant Human GBP1 Protein Pre-coupled Magnetic Beads HEK293 Human

    Involved Pathway

    GBP1 involved in several pathways and played different roles in them. We selected most pathways GBP1 participated on our site, such as Cytokine Signaling in Immune system,Immune System,Interferon Signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with GBP1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Immune System GM11711,MICA,EIF4E3,PAG1,CLEC4A,ADAR,NCKAP1,DEFB103A,TAX1BP1,DEFB116
    Type II interferon signaling (IFNG) IFIT2,Ifna,IFI6,REG1A
    Interferon gamma signaling GBP4,TRIM5,OASL,TRIM26,TRIM46,IRF4,GBP2,TRIM10,TRIM38,TRIM8
    Interferon Signaling TRIM68,GBP5,ARIH1L,USP18,TRIM22,ARIH1,TRIM5,GBP2,IRF9,TRIM31
    Cytokine Signaling in Immune system UBE2V1,TRIM46,NEFLB,TRIM8,TRIM3,PTPRA,ARIH1L,FRS2,IFI35,NOD1

    Protein Function

    GBP1 has several biochemical functions, for example, GTP binding,GTPase activity,Hsp90 protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GBP1 itself. We selected most functions GBP1 had, and list some proteins which have the same functions with GBP1. You can find most of the proteins on our site.

    Function Related Protein
    spectrin binding ADD2,SPTAN1,DYNC1I1,CAMSAP1,SLC26A5,EPB41,MYO7A,CAMSAP1L1,UNC13A,KIF3A
    GTP binding RAP1AB,ARL15,TUBA8L3,EIF5,NUDT2,ARHGAP35,TUFM,ERAS,TUBB2,GBP2
    cytokine binding KITA,Fzd4,NRP2,IL17F,ELANE,CSF1R,CXCR4,IL31RA,NRP1,LIFR
    protein binding KLHL22,ITGB3,RIOK3,CLTA,HSPB8,SNRPB2,MYCBP2,PSMB9,SASS6,RPS2
    Hsp90 protein binding NPAS2,RPS3,NASP,PPID,FKBP6,CSNK2A1,STUB1,ERBB2,HIF1A,AHR
    actin binding COBL,SPIRE2,ABRA,DMD,TWF2B,SPTAN1,SYN1,KCNMA1,MYO1C,SSH3
    enzyme binding TSPAN10,TULP3,ATG3,HIST1H2AL,YWHAE,WWOX,DVL1,HMGA1-RS1,PICK1,CNTNAP2
    identical protein binding AGER,TARDBP,ETNPPL,ORAI1,DLC,CLPP,AGXT2L2,RGMB,HSPB8,STAT6
    GTPase activity GNA15.4,TUBA4A,TUBAL3,MFN1,RAB40C,TUBA8L3,RHOT2,RAB3DB,GTPBP1,RAB42

    Interacting Protein

    GBP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GBP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of GBP1.

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    Resources

    Gene Families

    Cytokines
    Cytokines

    References

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