GBP1

  • Official Full Name

    guanylate binding protein 1, interferon-inducible

  • Overview

    Guanylate binding protein expression is induced by interferon. Guanylate binding proteins are characterized by their ability to specifically bind guanine nucleotides (GMP, GDP, and GTP) and are distinguished from the GTP-binding proteins by the presence of 2 binding motifs rather than 3.

  • Synonyms

    GBP1;guanylate binding protein 1, interferon-inducible;guanylate binding protein 1, interferon inducible, 67kDa;interferon-induced guanylate-binding protein 1;GBP-1;huGBP-1;GTP-binding protein 1;guanine nucleotide-binding protein 1;guanylate bindi

Recombinant Proteins

  • Human
  • Zebrafish
  • Pig
  • E.coli
  • Wheat Germ
  • Mammalian Cell
  • HEK293
  • Human Cell
  • In Vitro Cell Free System
  • Mammalian cells
  • HEK293T
  • GST
  • Non
  • His
  • Myc&DDK
  • Flag
  • His&Fc&Avi
Cat.# Product name Source (Host) Species Tag Protein Length Price
GBP1-13180H Recombinant Human GBP1, GST-tagged E.coli Human GST 242-592a.a.
GBP1-28991TH Recombinant Human GBP1 Wheat Germ Human Non 592 amino acids
GBP1-492Z Recombinant Zebrafish GBP1 Mammalian Cell Zebrafish His
GBP1-53H Recombinant Human GBP1 protein, His-tagged E.coli Human His 607aa
GBP1-6940H Recombinant Human GBP1 protein(Met1-Cys589), His-tagged HEK293 Human His 1-589 a.a.
GBP1-1686HCL Recombinant Human GBP1 cell lysate Human Cell Human Non
GBP1-13181H Recombinant Human GBP1 protein, His-tagged E.coli Human His 242-592 aa
GBP1-1324H Recombinant Human GBP1 Protein, MYC/DDK-tagged HEK293 Human Myc&DDK
GBP1-182HF Recombinant Full Length Human GBP1 Protein In Vitro Cell Free System Human Full L. 592 amino acids
GBP1-2023HFL Recombinant Full Length Human GBP1 Protein, C-Flag-tagged Mammalian cells Human Flag Full L.
GBP1-4776H Recombinant Human GBP1 Protein, GST-tagged Wheat Germ Human GST
GBP1-5522HF Recombinant Full Length Human GBP1 Protein, GST-tagged In Vitro Cell Free System Human GST Full L. 592 amino acids
GBP1-5526H Recombinant Human GBP1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Human Myc&DDK
GBP1-945P Recombinant Pig GBP1 Protein, His-tagged E.coli Pig His Lys35-Lys275
GBP1-968H Recombinant Human GBP1 Protein, His (Fc)-Avi-tagged HEK293 Human His&Fc&Avi
GBP1-968H-B Recombinant Human GBP1 Protein Pre-coupled Magnetic Beads HEK293 Human

    Involved Pathway

    GBP1 involved in several pathways and played different roles in them. We selected most pathways GBP1 participated on our site, such as Cytokine Signaling in Immune system,Immune System,Interferon Signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with GBP1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Interferon gamma signaling FCGR1B,GBP6,TRIM45,IRF4,TRIM14,GBP4,TRIM29,TRIM3,TRIM6,TRIM10
    Immune System BTR22,TRIM39,DHX9,UBR1,LAIR1,BTR16,ARIH1L,TRIM6,KPNA4,TREX1
    Interferon Signaling IRF6,SAMHD1,TRIM10,TRIM45,ADAR,IRF2,IRF9,IFIT2,ARIH1,IFIT10
    Type II interferon signaling (IFNG) IFI6,IFIT2,REG1A,Ifna
    Cytokine Signaling in Immune system OASL,SPTBN2,CSHL1,IFIT14,EIF4G2A,NUPL2,IFIT3,HLA-DQB2,JAK1,EDAR

    Protein Function

    GBP1 has several biochemical functions, for example, GTP binding,GTPase activity,Hsp90 protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GBP1 itself. We selected most functions GBP1 had, and list some proteins which have the same functions with GBP1. You can find most of the proteins on our site.

    Function Related Protein
    cytokine binding CSF1RA,CRLF1,IL31RA,ELANE,IFNGR1,KITA,CSF1R,CHRD,CNTFR,NRP1
    GTPase activity RHOF,RAB25A,RRAGCA,RAB5AB,TUBA4L,RND2,DIRAS3,SEPT9,RAB3DB,GNAS
    enzyme binding HIST1H2AE,KPNB1,RCOR2,PARP1,BIRC7,KRT79,NR5A1,SLC27A2,SPDL1,PARK7
    identical protein binding POLG2,SCHIP1,NPR2,LYZ,CCL4,PRDX1,SIRT1,ERBB2,BAX,APOE
    protein binding RBM39,TAPBP,UBE2K,CASR,RAB3C,CHRNB2,LDHAL6B,PDCL3,SNRPD3,HSPB2
    spectrin binding CAMSAP1,USH1G,DYNC1I1,MYO7A,USH1C,SPTAN1,UNC13A,KIF3A,SLC26A5,PTPRN
    Hsp90 protein binding AHR,UNC45B,USP19,ARNTL,TELO2,HDAC6,STUB1,RPS3,CHORDC1,ERN1
    GTP binding GNA11B,ARL4D,RAB27A,RAB40AL,RAB35B,GNL2,SEPT3,GLUD2,RHOJ,RIT2
    actin binding PHACTR3A,HIP1,HOOK1,FBXO25,NF2,SSH2,DAAM1B,SMYHC3,WASF2,MSN

    Interacting Protein

    GBP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GBP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of GBP1.

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    Resources

    Gene Families

    Cytokines
    Cytokines

    References

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