GAL
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Official Full Name
Gal galanin prepropeptide -
Overview
Galanin is small neuropeptide that functions as a cellular messenger within the central and peripheral nervous systems,;modulating diverse physiologic functions (Mechenthaler, 2008 (PubMed 18500643)). -
Synonyms
GAL;galanin prepropeptide;galanin peptides;Galn
Recombinant Proteins
- Mouse
- Rat
- Human
- Chicken
- E.coli
- Mammalian Cells
- Human Cells
- HEK293
- Wheat Germ
- In Vitro Cell Free System
- His&T7
- GST&His
- His
- Fc
- Non
- Avi&Fc&His
- GST
- DDK&Myc
- His&Myc
Involved Pathway
GAL involved in several pathways and played different roles in them. We selected most pathways GAL participated on our site, such as Class A/1 (Rhodopsin-like receptors),G alpha (i) signalling events,GPCR downstream signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with GAL were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Class A/1 (Rhodopsin-like receptors) | CCL35.2,INSL3,CCRL2,LTB4R,QRFP,ACKR4,CHRM1,CGA,OPN1MW2,GPR4 |
| G alpha (i) signalling events | CXCL11.8,DRD2,RGS7,FPR-RS3,FPR-RS6,TAS2R13,NPB,CCR3,RGR,RLN3A |
| Peptide ligand-binding receptors | HEBP1,GPR37L1,PYY,APLNR,KEL,TRH,PNOC,GPR37B,RXFP2,PNOCB |
| GPCR ligand binding | CCR3,PNOCB,PROKR1,GCGB,FZD10,GPR39,CCRL2,PYY,TAC3,INSL3 |
| Signal Transduction | RTKN,CXCR7B,GNA13B,TAC2,DSCAMA,NTS,ARHGAP17B,ARHGAP26,TAGAP,MAPK6 |
| Signaling by GPCR | HEBP1,GPR77,GPR31,GPRC6A,PRKCHB,RGS21,CCK,OXGR1A.2,PLEKHG2,OBSCN |
| GPCR downstream signaling | GPR132B,GRP,SST,GPRC6A,PROKR2,OXGR1,ARHGEF17,ADRA2C,UTS2D,PYY |
Protein Function
GAL has several biochemical functions, for example, galanin receptor activity,neuropeptide hormone activity,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GAL itself. We selected most functions GAL had, and list some proteins which have the same functions with GAL. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| type 2 galanin receptor binding | C12orf39 |
| neuropeptide hormone activity | QRFP,CRH,PPY,VIP,PYY,NTS,TRH,AVP,PNOC,AGRP |
| galanin receptor activity | GALR3,GALR2,GALR1 |
| protein binding | ATP6V0D2,SLC6A12,MICALL2,MYLK2,VTI1B,GABPA,ZSCAN21,BCL2L1,TSSK2,SOST |
| type 3 galanin receptor binding | C12orf39 |
Interacting Protein
GAL has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GAL here. Most of them are supplied by our site. Hope this information will be useful for your research of GAL.
SGTA;PREP1
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References
- Yang, J; Yang, F; et al. Water-soluble polysaccharide isolated with alkali from the stem of Physalis alkekengi L.: Structural characterization and immunologic enhancement in DNA vaccine. CARBOHYDRATE POLYMERS 121:248-253(2015).
- Pinson, ML; Waibel, KH; et al. Safe administration of a gelatin-containing vaccine in an adult with galactose-alpha-1,3-galactose allergy. VACCINE 33:1231-1232(2015).
