GAGE1
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Official Full Name
G antigen 1 -
Overview
This gene belongs to a family of genes that are expressed in a variety of tumors but not in normal tissues, except for the testis. The sequences of the family members are highly related but differ by scattered nucleotide substitutions. The antigenic peptide YRPRPRRY, which is also encoded by several other family members, is recognized by autologous cytolytic T lymphocytes. Nothing is presently known about the function of this protein. Alternative splicing results in multiple transcript variants. -
Synonyms
GAGE1;G antigen 1;cancer/testis antigen family 4;member 1;CT4.1;Cancer/testis antigen 4.1;CT4 1;GAGE 1;MZ2 F antigen;MZ2-F antigen;cancer/testis antigen family 4, member 1;GAGE-1
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| GAGE1-26549TH | Recombinant Human GAGE1 | Wheat Germ | Human | Non | 138 amino acids |
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| GAGE1-6050HCL | Recombinant Human GAGE1 293 Cell Lysate | HEK293 | Human | Non |
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| GAGE1-6051HCL | Recombinant Human GAGE1 293 Cell Lysate | HEK293 | Human | Non |
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| GAGE1-189HF | Recombinant Full Length Human GAGE1 Protein | In Vitro Cell Free System | Human | Full L. 138 amino acids |
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| GAGE1-4663H | Recombinant Human GAGE1 Protein, GST-tagged | Wheat Germ | Human | GST |
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| GAGE1-5211HF | Recombinant Full Length Human GAGE1 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 139 amino acids |
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Involved Pathway
GAGE1 involved in several pathways and played different roles in them. We selected most pathways GAGE1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with GAGE1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
GAGE1 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GAGE1 itself. We selected most functions GAGE1 had, and list some proteins which have the same functions with GAGE1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | DOCK4,SPAG5,NOS1AP,LRRFIP2,FAM46B,MEOX2,ULK3,MAPK1,DNAJC19,THAP3 |
Interacting Protein
GAGE1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GAGE1 here. Most of them are supplied by our site. Hope this information will be useful for your research of GAGE1.
MEOX2;FLJ13057
Resources
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References
- Misyurin, VA; Misyurin, AV; et al. Cancer-testis Gene Expression Profile in Human Melanoma Cell Lines. BIOLOGICHESKIE MEMBRANY 31:104-109(2014).
- Bode, PK; Thielken, A; et al. Cancer testis antigen expression in testicular germ cell tumorigenesis. MODERN PATHOLOGY 27:899-905(2014).
