Gabrg2
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Official Full Name
gamma-aminobutyric acid (GABA) A receptor, gamma 2 -
Overview
Phosphopeptide corresponding to amino acid residues surrounding the phospho-Ser327 of the GABAA receptor, γ2 subunit. -
Synonyms
GABRG2;gamma-aminobutyric acid (GABA) A receptor, gamma 2;gamma-aminobutyric acid receptor subunit gamma-2;GABA(A) receptor subunit gamma-2;gamma-aminobutyric acid A receptor, gamma 2;gamma-aminobutyric acidA receptor, gamma 2;gamma-aminobutyric aci
Recombinant Proteins
- Human
- Rhesus macaque
- Rat
- Mouse
- Chicken
- Zebrafish
- E.coli
- Mammalian Cells
- HEK293
- His
- Non
- Avi
- Fc
Involved Pathway
Gabrg2 involved in several pathways and played different roles in them. We selected most pathways Gabrg2 participated on our site, such as Neuroactive ligand-receptor interaction,Retrograde endocannabinoid signaling,GABAergic synapse, which may be useful for your reference. Also, other proteins which involved in the same pathway with Gabrg2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Retrograde endocannabinoid signaling | GABRB1,GNB1,GABRA6,PRKCG,NAPEPLD,FAAH,GNB4,GNG5,GRIA2,GNAI1 |
| Neuroactive ligand-receptor interaction | OPRL1,GRIK1,CHRM2A,P2RX3A,PRLHR2B,MAS1,HTR5A,CSH2,GLRBB,PTGER2A |
| Nicotine addiction | GABRB2,GABRP,GABRE,GABRG3,GABRB1,CHRNA6,GRIN2B,GRIA1,GRIN2D,GABRR3 |
| GABAergic synapse | GNGT1,GABRE,SLC12A5,GABRB3,SRC,GNGT2,GNB3,GPHN,PRKACG,GABBR1 |
Protein Function
Gabrg2 has several biochemical functions, for example, contributes_to GABA-A receptor activity,GABA-A receptor activity,benzodiazepine receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by Gabrg2 itself. We selected most functions Gabrg2 had, and list some proteins which have the same functions with Gabrg2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| chloride channel activity | TTYH3B,CLCA5,CLCNKB,GABRA2,CLCA1,SLC26A9,GABRR3,APOL1,CLCA3,CLIC5B |
| protein binding | C10orf33,USP8,TCEB3,IPO7,OLFM4,SOX14,IFT172,RBP4,GSN,BCAP31 |
| contributes_to GABA-A receptor activity | GABRR3A,GABRA2,GABRG3,GABRZ,GABRG1,GABRA3,GABRA4,GABRQ,GABRA6A,GABRR2A |
| inhibitory extracellular ligand-gated ion channel activity | GABRA6A,GABRB2,GABRA1,GABRA5,GABRG1,GABRE,GABRG3,GABRA3,GABRA4,GABRA6 |
| GABA-A receptor activity | GABRB3,GABRA1,GABRB1,GABRD,GABRR2,GABRB2,GABRE,GABRR1,GABRZ,GABRR2A |
| benzodiazepine receptor activity | GABRA6,TSPO,GABRA3,GABRA4,GABRA2 |
Interacting Protein
Gabrg2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Gabrg2 here. Most of them are supplied by our site. Hope this information will be useful for your research of Gabrg2.
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References
- Richard, CD; Tanenbaum, A; et al. SWDreader: A wavelet-based algorithm using spectral phase to characterize spike-wave morphological variation in genetic models of absence epilepsy. JOURNAL OF NEUROSCIENCE METHODS 242:127-140(2015).
- Schubert, J; Siekierska, A; et al. Mutations in STX1B, encoding a presynaptic protein, cause fever-associated epilepsy syndromes. NATURE GENETICS 46:1327-1332(2014).
