Gabra4
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Official Full Name
gamma-aminobutyric acid (GABA) A receptor, alpha 4 -
Synonyms
GABRA4;gamma-aminobutyric acid (GABA) A receptor, alpha 4;gamma-aminobutyric acid receptor subunit alpha-4;GABA(A) receptor;alpha 4;GABA(A) receptor, alpha 4
Recombinant Proteins
- Human
- Rat
- Mammalian Cells
- HEK293
- E.coli
- Wheat Germ
- In Vitro Cell Free System
- His
- Non
- His&GST
- His&Fc&Avi
- GST
- His&SUMO
Involved Pathway
Gabra4 involved in several pathways and played different roles in them. We selected most pathways Gabra4 participated on our site, such as Neuroactive ligand-receptor interaction,Retrograde endocannabinoid signaling,GABAergic synapse, which may be useful for your reference. Also, other proteins which involved in the same pathway with Gabra4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| GABAergic synapse | GNAI1,SLC38A1,GLS2,GNB3,PRKCA,HAP1,GPHN,GABRB3,PRKCB,GABRA6 |
| Nicotine addiction | GABRA5,GABRR2,GRIN2B,SLC17A7,GABRG1,GRIA1,GRIN2A,GRIA4,GABRA2,GABRB2 |
| Retrograde endocannabinoid signaling | PRKCB,GNG3,GABRG2,GNB3,GNG8,MAPK12,GABRQ,GABRA3,MAPK3,MAPK9 |
| Neuroactive ligand-receptor interaction | PTGER2B,ADRB2A,P2RX3B,GRIK1,PTGER3,AVPR1B,CHRM5B,TRY,GALR3,GABRA6 |
Protein Function
Gabra4 has several biochemical functions, for example, contributes_to GABA-A receptor activity,benzodiazepine receptor activity,chloride channel activity. Some of the functions are cooperated with other proteins, some of the functions could acted by Gabra4 itself. We selected most functions Gabra4 had, and list some proteins which have the same functions with Gabra4. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| contributes_to GABA-A receptor activity | GABRG1,GABRQ,GABRG2,GABRA6,GABRR3A,GABRA6A,GABRG3,GABRR2A,GABRA5,GABRZ |
| inhibitory extracellular ligand-gated ion channel activity | GABRB2,GABRA6,GABRA3,GABRA6A,GABRA1,GABRA2,GABRG2,GABRE,GABRG1,GABRA5 |
| benzodiazepine receptor activity | GABRA2,GABRA3,GABRA6,TSPO,GABRG2 |
| chloride channel activity | GABRA2,SLC26A4,CLIC2,CLIC3,SLC1A4,GABRE,GABRG2,GABRR1,SLC26A7,CLIC5B |
Interacting Protein
Gabra4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Gabra4 here. Most of them are supplied by our site. Hope this information will be useful for your research of Gabra4.
DGAT1
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References
- Srivastava, S; Cohen, J; et al. A Novel Variant in GABRB2 Associated with Intellectual Disability and Epilepsy. AMERICAN JOURNAL OF MEDICAL GENETICS PART A 164A:2914-2921(2014).
- Quadrato, G; Elnaggar, MY; et al. Modulation of GABAA Receptor Signaling Increases Neurogenesis and Suppresses Anxiety through NFATc4. JOURNAL OF NEUROSCIENCE 34:8630-8645(2014).
