GABARAPL1
-
Official Full Name
GABA(A) receptor-associated protein like 1 -
Synonyms
GABARAPL1;GABA(A) receptor-associated protein like 1;gamma-aminobutyric acid receptor-associated protein-like 1;APG8L;ATG8B;ATG8L;gec1;APG8 like;ATG8;Early estrogen regulated protein;GABA;GABA(A) receptor associated protein like 1;Gamma aminobutyric acid receptor associated protein like 1;GEC 1;Glandular epithelial cell protein 1;GEC-1;early estrogen-regulated protein;GABA(A) receptor-associated protein-like 1;APG8-LIKE
Recombinant Proteins
- Rhesus macaque
- Rat
- Human
- Mouse
- Mammalian Cell
- E.coli
- HEK293
- E. coli
- His
- His&Fc&Avi
- GST
Involved Pathway
GABARAPL1 involved in several pathways and played different roles in them. We selected most pathways GABARAPL1 participated on our site, such as FoxO signaling pathway,Regulation of autophagy,GABAergic synapse, which may be useful for your reference. Also, other proteins which involved in the same pathway with GABARAPL1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| GABAergic synapse | GABRE,GABARAPL2,GABRR2,GABRA2,GNG5,GNG7,SLC12A5,PRKACB,GABRA4,SLC6A1 |
| FoxO signaling pathway | INS2,IGF1R,STK11,SMAD3A,PTEN,GADD45AB,MAP2K2B,CDKN2D,ATM,BCL6 |
| Regulation of autophagy | PIK3C3,ATG4D,PRKAA2,ATG14,INS1,IFNA12,PRKAA1,IFNA5,GABARAP,PIK3R4 |
Protein Function
GABARAPL1 has several biochemical functions, for example, GABA receptor binding,Tat protein binding,beta-tubulin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GABARAPL1 itself. We selected most functions GABARAPL1 had, and list some proteins which have the same functions with GABARAPL1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | CCK,PRL2C2,PRMT3,RIN3,HIST1H3A,STUB1,PIANP,GLYR1,GALNT3,NFKB2 |
| GABA receptor binding | PPP2CA,GABARAPL2,GABARAPA,JAKMIP1,AKAP5,GABRB1,GABARAP,MAF1,GABRA5,PLCL2 |
| beta-tubulin binding | GABARAP,ARL8A,LRPPRC,PDCD5,B4GALT1,PACRG,TRPV4,ADNP,HDAC6,FGF13 |
| microtubule binding | KIF2B,GABARAP,KATNAL2,REEP4,MACF1,MAPT,CHD4,KIF3C,KCNH2A,NUMA1 |
| ubiquitin protein ligase binding | RELA,UBE2A,CDC34B,UBE2W,TMEM189,POLR2A,PINK1,FZD8,AURKA,SCN5A |
| Tat protein binding | SMARCA4,NPM1,SMARCB1,MDFIC,ACTB,DLL1,TRIM32 |
Interacting Protein
GABARAPL1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GABARAPL1 here. Most of them are supplied by our site. Hope this information will be useful for your research of GABARAPL1.
SQSTM1;NBR1;SQSTM1;IPO5;GBAS
Resources
Related Services
Related Products
References
- Jin, ZS; Zheng, L; et al. Upregulation of forkhead box O3 transcription is involved in C2-ceramide induced apoptosis and autophagy in ovarian cancer cells in vitro. MOLECULAR MEDICINE REPORTS 10:3099-3105(2014).
- Ochaba, J; Lukacsovich, T; et al. Potential function for the Huntingtin protein as a scaffold for selective autophagy. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 111:16889-16894(2014).
