G6PC3
-
Official Full Name
glucose 6 phosphatase, catalytic, 3 -
Synonyms
SCN4;UGRP
Recombinant Proteins
- Rhesus macaque
- Rat
- Zebrafish
- Mouse
- Human
- zebrafish
- Mammalian Cells
- HEK293
- Wheat Germ
- In Vitro Cell Free System
- E.coli
- His
- His&Fc&Avi
- GST
Involved Pathway
G6PC3 involved in several pathways and played different roles in them. We selected most pathways G6PC3 participated on our site, such as Glycolysis / Gluconeogenesis,Galactose metabolism,Starch and sucrose metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with G6PC3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| PIK-Akt signaling pathway | GNB4,FGF5,IL2RB,KLK1B4,TRP53,Il6ra,GNG10,SGK1,IL6R,GNG3 |
| Starch and sucrose metabolism | UGT1A6,UGP2,UGT2A3,G6PC2,GBE1,GPI1,UGT1A2,PGM2L1,GPI,UGP2A |
| Insulin signaling pathway | PRKAB1A,PYGL,CALM1B,MKNK1,HK1,INS2,RHEB,CALM2B,FLOT2,MAPK10 |
| AMPK signaling pathway | TBC1D1,PPP2R2C,PIK3R5,PPARG,CREB5,RAB11B,PPP2R5B,PPP2CB,AKT2,INS1 |
| Insulin resistance | AKT3A,SLC2A2,CREB3L3,G6PC2,PRKAB1,PPP1CB,CREB3L2,PIK3R2,SOCS3B,SLC27A1A |
| Metabolic pathways | CYP2C8,CYP2P6,HSD17B7,ST6GAL1,PIGU,NT5C3L,ACSL3B,FH1,SMPD2,ATP5G3B |
| Adipocytokine signaling pathway | ADIPOQ,MAPK9,NFKB1,MTOR,ADIPOR1B,MAPK8A,PTPN11,LEP,AKT2,SLC2A1 |
| Carbohydrate digestion and absorption | ATP1A1,AMY2A4,AKT2,G6PC2,FXYD2,PIK3R3,ATP1B2,ATP1A4,SLC2A5,AMY2A3 |
| Galactose metabolism | UGP2B,GALK1,HK2,PFKMB,GAA,aLA,GLA,PFKMA,UGP2A,B4GALT1 |
Protein Function
G6PC3 has several biochemical functions, for example, glucose-6-phosphatase activity,hydrolase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by G6PC3 itself. We selected most functions G6PC3 had, and list some proteins which have the same functions with G6PC3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| glucose-6-phosphatase activity | G6PCA.1,G6PC,G6PC2,G6PCA.2 |
| hydrolase activity | FAM105B,KLK1B5,PPAPDC3,AGBL4,SMG6,C1rb,ATP1A1A.2,INPPL1A,HAGHL,MMP13A |
Interacting Protein
G6PC3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with G6PC3 here. Most of them are supplied by our site. Hope this information will be useful for your research of G6PC3.
Resources
Related Services
Related Products
References
- Arikoglu, T; Kuyucu, N; et al. A novel G6PC3 gene mutation in severe congenital neutropenia: pancytopenia and variable bone marrow phenotype can also be part of this syndrome. EUROPEAN JOURNAL OF HAEMATOLOGY 94:79-82(2015).
- Lin, SR; Pan, CJ; et al. Functional analysis of mutations in a severe congenital neutropenia syndrome caused by glucose-6-phosphatase-beta deficiency. MOLECULAR GENETICS AND METABOLISM 114:41-45(2015).
