FSTL1
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Official Full Name
follistatin-like 1 -
Overview
This gene encodes a protein with similarity to follistatin, an activin-binding protein. It contains an FS module, a follistatin-like sequence containing 10 conserved cysteine residues. This gene product is thought to be an autoantigen associated with rheumatoid arthritis. -
Synonyms
FSTL1;follistatin-like 1;follistatin-related protein 1;FRP;FSL1;follistatin-like protein 1;FLJ50214;FLJ52277
Recombinant Proteins
- Human
- Rhesus macaque
- Rat
- Mouse
- Chicken
- HEK293
- E.coli
- Mammalian Cells
- Human Cells
- Wheat Germ
- In Vitro Cell Free System
- His
- Non
- T7
- GST
- Fc
- His&Fc&Avi
- Flag
- His&GST
- Myc&DDK
Involved Pathway
FSTL1 involved in several pathways and played different roles in them. We selected most pathways FSTL1 participated on our site, such as Signal Transduction,Signaling by BMP, which may be useful for your reference. Also, other proteins which involved in the same pathway with FSTL1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Signal Transduction | ACKR4,EDNRAB,ABHD12,OTUD7B,CALML4,UCHL5,TULP3,INSL5,ARHGAP12,RDH12 |
| Signaling by BMP | CHRDL1,CALML4,NOG1,FSTL1B,SKIA,NOG,GREM2,FSTL1A,SKIB |
Protein Function
FSTL1 has several biochemical functions, for example, calcium ion binding,heparin binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FSTL1 itself. We selected most functions FSTL1 had, and list some proteins which have the same functions with FSTL1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | ABCB1,AHCY,PAX8,FAM21C,MED21,EDNRB,CFL1,XRCC4,BTG2,GNAI3 |
| heparin binding | APOB,WISP3,AZU1,CCL2,BMP4,CCL15,FMODA,WISP1A,PLA2G2D,ADAMTS3 |
| calcium ion binding | F9A,SLC25A25,EFHA1,AOC3,ANXA3A,EMR1,RCVRN,SYT6,CDH10,CALM1 |
Interacting Protein
FSTL1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FSTL1 here. Most of them are supplied by our site. Hope this information will be useful for your research of FSTL1.
APPBP2;CD14;DIP2A;INHBA;TGFB1;BMP2;CRK
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References
- Dong, YY; Geng, Y; et al. Blocking follistatin-like 1 attenuates bleomycin-induced pulmonary fibrosis in mice. JOURNAL OF EXPERIMENTAL MEDICINE 212:235-252(2015).
- Campfield, BT; Nolder, CL; et al. Follistatin-like protein 1 is a critical mediator of experimental Lyme arthritis and the humoral response to Borrelia burgdorferi infection. MICROBIAL PATHOGENESIS 73:70-79(2014).
