FOXI1
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Official Full Name
forkhead box I1 -
Overview
This gene belongs to the forkhead family of transcription factors which is characterized by a distinct forkhead domain. The specific function of this gene has not yet been determined; however, it is possible that this gene plays an important role in the development of the cochlea and vestibulum, as well as embryogenesis. Mutations in this gene may be associated with the common cavity phenotype. Two transcript variants encoding different isoforms have been found for this gene. -
Synonyms
FOXI1;forkhead box I1;forkhead box protein I1;forkhead homolog 10;HNF-3/forkhead homolog 3;Hfh3;Fkh10;HFH-3;FREAC6;5830401E05Rik
Recombinant Proteins
- Human
- Zebrafish
- Mouse
- Mammalian Cells
- HEK293
- E.coli
- Wheat Germ
- In Vitro Cell Free System
- His
- Non
- His&Fc&Avi
- Myc&DDK
- GST
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| FOXI1-513H | Recombinant Human FOXI1 | Mammalian Cells | Human | His |
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| FOXI1-9633Z | Recombinant Zebrafish FOXI1 | Mammalian Cells | Zebrafish | His |
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| FOXI1-6155HCL | Recombinant Human FOXI1 293 Cell Lysate | HEK293 | Human | Non |
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| Foxi1-1520M | Recombinant Mouse Foxi1 Protein, His-tagged | E.coli | Mouse | His | Met1-Asp173 |
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| FOXI1-2564H | Recombinant Human FOXI1 Protein, His-tagged | E.coli | Human | His |
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| FOXI1-2969H | Recombinant Human FOXI1 Protein, His (Fc)-Avi-tagged | HEK293 | Human | His&Fc&Avi |
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| FOXI1-2969H-B | Recombinant Human FOXI1 Protein Pre-coupled Magnetic Beads | HEK293 | Human |
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| Foxi1-3072M | Recombinant Mouse Foxi1 Protein, Myc/DDK-tagged | HEK293 | Mouse | Myc&DDK |
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| FOXI1-4454H | Recombinant Human FOXI1 Protein, GST-tagged | Wheat Germ | Human | GST |
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| FOXI1-4576H | Recombinant Human FOXI1 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293 | Human | Myc&DDK |
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| FOXI1-5074HF | Recombinant Full Length Human FOXI1 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 283 amino acids |
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Involved Pathway
FOXI1 involved in several pathways and played different roles in them. We selected most pathways FOXI1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with FOXI1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
FOXI1 has several biochemical functions, for example, DNA binding, bending,RNA polymerase II core promoter proximal region sequence-specific DNA binding,sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FOXI1 itself. We selected most functions FOXI1 had, and list some proteins which have the same functions with FOXI1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| sequence-specific DNA binding | ZFP42,PPARDB,HOXA9B,ZFP161,NR1D4B,KLF5,DLX3,CAMTA2,E2F5,FOXD5 |
| transcription factor activity, sequence-specific DNA binding | THRB,POU1F1,ZNF445,BCL3,ZNF812,TSC22D2,FOXD5,FOXH1,CNOT8,PRRX2 |
| DNA binding, bending | HMGA2,TFAM,GATA1,TOP2B,HHEX,TOP2A,LEF1,FOXD4,CRIP1,HMGB1 |
| RNA polymerase II core promoter proximal region sequence-specific DNA binding | RBPJL,ELF4,NR3C1,ZSCAN21,NR2C1,OVOL1,FUBP3,SIX1,TFE3,RAX |
| transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding | TFE3B,HOXD13,HOXC11,SMAD4,ELK3,TFE3,DBP,RELA,MEF2C,ELF1 |
| transcription regulatory region DNA binding | TFEB,SNCA,TBX21,TP63,BRD7,GATA5,HDAC1,GATA6,ARID4A,TAF2 |
Interacting Protein
FOXI1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FOXI1 here. Most of them are supplied by our site. Hope this information will be useful for your research of FOXI1.
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References
- Zhang, H; Wang, XL; et al. Time Point-Based Integrative Analyses of Deep-Transcriptome Identify Four Signal Pathways in Blastemal Regeneration of Zebrafish Lower Jaw. STEM CELLS 33:806-818(2015).
- Roy, A; Al-Bataineh, MM; et al. Collecting Duct Intercalated Cell Function and Regulation. CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY 10:305-324(2015).
