FMNL2
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Official Full Name
formin-like 2 -
Overview
This gene encodes a formin-related protein. Formin-related proteins have been implicated in morphogenesis, cytokinesis, and cell polarity. Alternatively spliced transcript variants encoding different isoforms have been described but their full-length nature has yet to be determined. -
Synonyms
FMNL2;formin-like 2;FHOD2, formin homology 2 domain containing 2;formin-like protein 2;KIAA1902;FHOD2;Formin homology 2 domain containing protein 2;Formin like protein 2;OTTHUMP00000204908;formin homology 2 domain containing 2;formin homology 2 domain-containing protein 2
Recombinant Proteins
- Mouse
- Human
- Mammalian Cell
- HEK293
- HEK293T
- Wheat Germ
- In Vitro Cell Free System
- His
- Myc&DDK
- His&Fc&Avi
- GST
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| FMNL2-5935M | Recombinant Mouse FMNL2 Protein | Mammalian Cell | Mouse | His |
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| FMNL2-2431H | Recombinant Human FMNL2 Protein, MYC/DDK-tagged | HEK293 | Human | Myc&DDK |
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| Fmnl2-3051M | Recombinant Mouse Fmnl2 Protein, Myc/DDK-tagged | HEK293T | Mouse | Myc&DDK |
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| FMNL2-3287M | Recombinant Mouse FMNL2 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| FMNL2-3287M-B | Recombinant Mouse FMNL2 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| FMNL2-4390H | Recombinant Human FMNL2 Protein, GST-tagged | Wheat Germ | Human | GST |
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| FMNL2-4984HF | Recombinant Full Length Human FMNL2 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 178 amino acids |
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Involved Pathway
FMNL2 involved in several pathways and played different roles in them. We selected most pathways FMNL2 participated on our site, such as RHO GTPase Effectors,RHO GTPases Activate Formins,Signal Transduction, which may be useful for your reference. Also, other proteins which involved in the same pathway with FMNL2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| RHO GTPase Effectors | CLIP1,LIN7B,MKL1B,RHPN1,PRC1,NCKIPSD,NOXA1,IQGAP3,NDEL1B,FMNL1 |
| RHO GTPases Activate Formins | SPC25,PMF1,NSL1,NDEL1A,NUF2,MIS12,ZWILCH,CCDC99,NDEL1B,MKL1B |
| Signal Transduction | OPN1SW1,AKR1C6,KEL,MLN,TAGAPA,CSNK1G2,ABI1B,ROR1,ACKR4,LRP12 |
| Signaling by Rho GTPases | TAX1BP3,RHOF,ARHGAP22,RHOV,STARD8,ARHGAP9,ARHGAP29B,ARHGAP6,ARHGAP28,ARAP1 |
Protein Function
FMNL2 has several biochemical functions, for example, Rho GTPase binding,actin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FMNL2 itself. We selected most functions FMNL2 had, and list some proteins which have the same functions with FMNL2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| actin binding | FSCN2A,AFAP1,SPTBN2,LRRK2,FHOD1,VMHC,SSH3,CNN3,KLHL33,TNS1 |
| Rho GTPase binding | RHOH,FLNA,IQGAP3,ARHGEF16,DIAP1,ROCK2B,DAAM1,ECT2,ROCK2A,AKAP13 |
Interacting Protein
FMNL2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FMNL2 here. Most of them are supplied by our site. Hope this information will be useful for your research of FMNL2.
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