Fgfbp3
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Official Full Name
Fibroblast Growth Factor Binding Protein 3 -
Overview
Fibroblast growth factors, or FGFs, are a family of growth factors, with members involved in angiogenesis, wound healing, embryonic development and various endocrine signaling pathways. The FGFs are heparin-binding proteins and interactions with cell-surface-associated heparan sulfate proteoglycans have been shown to be essential for FGF signal transduction. FGFs are key players in the processes of proliferation and differentiation of wide variety of cells and tissues. -
Synonyms
Fibroblast Growth Factor Binding Protein 3;FGFBP3
Recombinant Proteins
- Human
- Mouse
- Insect Cell
- Mammalian Cell
- HEK293 cells
- HEK293
- Wheat Germ
- In Vitro Cell Free System
- His
- Non
- His&Fc&Avi
- GST
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| FGFBP3-267H | Recombinant Human FGFBP3 Protein, His-tagged | Insect Cell | Human | His | 1-258 a.a. |
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| FGFBP3-5859M | Recombinant Mouse FGFBP3 Protein | Mammalian Cell | Mouse | His |
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| FGFBP3-421HCL | Recombinant Human FGFBP3 cell lysate | Insect Cell | Human | Non |
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| FGFBP3-15H | Recombinant Human FGFBP3 Protein, His-tagged | HEK293 cells | Human | His | 28-258 a.a. |
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| FGFBP3-3240M | Recombinant Mouse FGFBP3 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| FGFBP3-3240M-B | Recombinant Mouse FGFBP3 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| FGFBP3-4120H | Recombinant Human FGFBP3 Protein, GST-tagged | Wheat Germ | Human | GST |
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| FGFBP3-4843HF | Recombinant Full Length Human FGFBP3 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 258 amino acids |
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Involved Pathway
Fgfbp3 involved in several pathways and played different roles in them. We selected most pathways Fgfbp3 participated on our site, such as FGFR2 ligand binding and activation,FGFR2b ligand binding and activation,Signal Transduction, which may be useful for your reference. Also, other proteins which involved in the same pathway with Fgfbp3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Signaling by FGFR | KAL1A,KAL1,FGFBP2,FGFBP1 |
| FGFR2 ligand binding and activation | FGFBP2,FGFBP1 |
| FGFR2b ligand binding and activation | FGFBP1,FGFBP2 |
| Signaling by FGFR2 | FGFBP2,FGFBP1 |
| Signal Transduction | GPR132,RHOT2,CALCB,RGS20,APOA4B.2,CLPS,ARHGAP29,ASH2L,RBP2A,PDK2 |
Protein Function
Fgfbp3 has several biochemical functions, for example, fibroblast growth factor binding,heparin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by Fgfbp3 itself. We selected most functions Fgfbp3 had, and list some proteins which have the same functions with Fgfbp3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| heparin binding | SMOC2,CXCL11,NAV2,CXCL13,FBLN7,RSPO2,PF4,SLIT1B,WISP1A,CFH |
| fibroblast growth factor binding | FGFR2,KLB,GPC1,FGFR1,FGFRL1,Api5,PTPRZ1,RPS2,GLG1,SCN5A |
Interacting Protein
Fgfbp3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Fgfbp3 here. Most of them are supplied by our site. Hope this information will be useful for your research of Fgfbp3.
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References
- Dudognon, B; Romero-Santacreu, L; et al. Production of functional active human growth factors in insects used as living biofactories. JOURNAL OF BIOTECHNOLOGY 184:229-239(2014).
- Hu, XL; Li, N; et al. Effects of integrin alpha(v)beta(3) on differentiation and collagen synthesis induced by connective tissue growth factor in human hypertrophic scar fibroblasts. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE 34:1323-1334(2014).
