Creative BioMart to Present at BPS 2025 Annual Meeting | February 15-19, 2025 Learn More

FAM84B

Official Full Name

family with sequence similarity 84, member B
Overview

FAM84B belongs to the FAM84 family. It is expressed in esophageal squamous cell carcinomas.
Synonyms

FAM84B; family with sequence similarity 84, member B; protein FAM84B; BCMP101; breast cancer membrane associated protein 101; neurological/sensory 2; NSE2; BF642811; D330050I23Rik; Breast cancer membrane protein 101; Breast cancer membrane-associated protein 101; FA84B_HUMAN; Family with sequence similarity 84 member B; OTTHUMP00000228215; Protein NSE2; RGD1562236;

Type

Recombinant Proteins
Cell & Tissue Lysates

Species

Human
Zebrafish

Source

E.coli
HEK293
In Vitro Cell Free System
Mammalian Cell
Wheat Germ

Tag

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	FAM84B-3809H	Recombinant Human FAM84B Protein, GST-tagged	Wheat Germ	GST		Inquiry
Human	FAM84B-12729H	Recombinant Human FAM84B, His-tagged	E.coli	His	1-310a.a.	$319 / 25μg
Human	FAM84B-2442H	Recombinant human FAM84B, His-tagged	E.coli	His		Inquiry
Human	FAM84B-6342HCL	Recombinant Human FAM84B 293 Cell Lysate	HEK293	Non		Inquiry
Human	FAM84B-4648HF	Recombinant Full Length Human FAM84B Protein, GST-tagged	In Vitro Cell Free System	GST	310 amino acids	Inquiry
Zebrafish	FAM84B-3992Z	Recombinant Zebrafish FAM84B	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein
Other Resource

FAM84B involved in several pathways and played different roles in them. We selected most pathways FAM84B participated on our site, such as Aflatoxin B1 metabolism, Aflatoxin activation and detoxification, Benzo(a)pyrene metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with FAM84B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Aflatoxin B1 metabolism	FAM84B;CYP2A13;CYP1A2;PRKRA;CYP3A4
Aflatoxin activation and detoxification	ACY3.1;CYP1A2;CYP2A13;ACY3;CYP3C4;CYP2Y3;FAM84B;GGTLC1;DPEP1
Benzo(a)pyrene metabolism	CYP3A4;FAM84B;AKR1C4;AKR1C2;CYP1A1;AKR1A1;CYP1B1
Bile secretion	SLC10A1;FAM84B;SLC27A5;ABCG2;SLC9A1;OSTB;SULT2A1;CYP7A1;SLC4A4
Biological oxidations	ADH8B;CYP2A6;CYP19A1;CYP11A1;CYP2C8;AADAC;AHCY;FDX1;CYP2C19
Chemical carcinogenesis	UGT2B7;Nat3;CCBL2;HSD11B1;CYP3A25;CCBL1;GSTM1;CYP2C19;UGT1A6B
Cytochrome P450 - arranged by substrate type	CYP4T8;POMCB;CYP3A5;CYP2B6;CYP2A6;CYP2U1;CYP2J2;CYP27B1;CYP2K6

FAM84B has several biochemical functions, for example, aromatase activity, caffeine oxidase activity, enzyme binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FAM84B itself. We selected most functions FAM84B had, and list some proteins which have the same functions with FAM84B. You can find most of the proteins on our site.

Function	Related Protein
aromatase activity	CYP19A1;CYP2S1;CYP4A12A;CYP2H1;CYP1D1;FAM84B;CYP3A4;CYP3A25;CYP2A12
caffeine oxidase activity	CYP3A4;CYP2C39;CYP2C9;FAM84B;CYP2C38;CYP1A2
enzyme binding	TRIO;ZFHX3;SCN5A;HIST1H2AI;RAD9;H2AFX;TRAF2;CYP2A6;Ar
heme binding	NOS2;CYP2E1;HBG1;CYP2B19;CYP2H1;HBAA1;CYP2F1;SDHDA;CYP2D6
iron ion binding	CYP2E1;CYP3C1L2;SC5DL;EGLN1;CYP24A1;TYW5;CYP27B1;CYP3A4;NOS2B
monooxygenase activity	CYP1A1;CYP4F3;CYP4T8;CYP2D6;CYP17A2;CYP2X8;CYP2C39;BCO1;CYP2F1
oxidoreductase activity	AIFM3;CREG2;CYP2P9;TDO2B;Aldh1a7;H2-KE6;OXNAD1;ADI1;PDHA1B
oxygen binding	TDO2;CYGB1;CYP2AD3;CYP2B6;CYP2R1;HBE;CYGB2;CYP2J5;CYP2U1
quinine 3-monooxygenase activity	CYP3A4;FAM84B
steroid binding	PAQR7A;PAQR7;NR3C1;UGT1A1;PGRMC2;ESRRB;SERPINA6;PAQR5;ESRRGA
steroid hydroxylase activity	CYP2C37;CYP3A4;CYP2K6;CYP2C9;CYP2X9;CYP2X8;CYP2B6;CYP2C18;CYP2AA12
taurochenodeoxycholate 6alpha-hydroxylase activity	CYP3A4;FAM84B
testosterone 6-beta-hydroxylase activity	CYP3A25;CYP3A41A;CYP3A4;FAM84B;CYP3A41B
vitamin D 24-hydroxylase activity	CYP1A1;FAM84B;CYP3A4
vitamin D3 25-hydroxylase activity	CYP3A4;CYP27A1;CYP2R1;FAM84B

FAM84B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FAM84B here. Most of them are supplied by our site. Hope this information will be useful for your research of FAM84B.

UROD; CHEK2; RAD51; XRCC3; BAG4; PTPN1; FGFR4; NOTCH2; SMAD4; PALB2; ESR2

Research Area

Du, MJ; Yuan, TZ; et al. Prostate cancer risk locus at 8q24 as a regulatory hub by physical interactions with multiple genomic loci across the genome. HUMAN MOLECULAR GENETICS 24:154-166(2015).

Ji, W; Bian, ZH; et al. Expulsion of micronuclei containing amplified genes contributes to a decrease in double minute chromosomes from malignant tumor cells. INTERNATIONAL JOURNAL OF CANCER 134:1279-1288(2014).