FAM189B
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Official Full Name
family with sequence similarity 189, member B -
Overview
This gene is located near the gene for the lysosomal enzyme glucosylceramidase; a deficiency in this enzyme is associated with Gaucher disease. The encoded protein has been identified as a potential binding partner of a WW domain-containing protein which is involved in apoptosis and tumor suppression. Alternative splicing results in multiple transcript variants. -
Synonyms
FAM189B;family with sequence similarity 189, member B;C1orf2, chromosome 1 open reading frame 2;protein FAM189B;cote1;C1orf2;Chromosome 1 open reading frame 2;Family with sequence similarity 189 member B;Hypothetical protein LOC10712
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| FAM189B-5556M | Recombinant Mouse FAM189B Protein | Mammalian Cells | Mouse | His |
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| FAM189B-6396HCL | Recombinant Human FAM189B 293 Cell Lysate | HEK293 | Human | Non |
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| FAM189B-3029M | Recombinant Mouse FAM189B Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| FAM189B-3029M-B | Recombinant Mouse FAM189B Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| RFL31503HF | Recombinant Full Length Human Protein Fam189B(Fam189B) Protein, His-Tagged | E.coli | Human | His | Full L. Full Length (1-668) |
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| RFL36668MF | Recombinant Full Length Mouse Protein Fam189B(Fam189B) Protein, His-Tagged | E.coli | Mus musculus | His | Full L. Full Length (1-669) |
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Involved Pathway
FAM189B involved in several pathways and played different roles in them. We selected most pathways FAM189B participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with FAM189B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
FAM189B has several biochemical functions, for example, WW domain binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FAM189B itself. We selected most functions FAM189B had, and list some proteins which have the same functions with FAM189B. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | PITPNM3,BEX2,CD27,GCKR,SPZ1,GCC2,ZMAT2,ATP11C,HIST2H3C2,PEX5 |
| WW domain binding | TRAF4,TNK2,TCEAL3,TCEAL2,SHISA5,TCEAL7,NDFIP2,TRP63,WBP5,KIF20B |
Interacting Protein
FAM189B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FAM189B here. Most of them are supplied by our site. Hope this information will be useful for your research of FAM189B.
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