ERI1
-
Official Full Name
exoribonuclease 1 -
Overview
THEX1 (3'hExo) is a 3' exonuclease that may play a role in the degradation of histone mRNA transcripts. A recently identified member of the DEDDh 3 exonuclease family, THEX1 binds the conserved stem-loop structure found at the 3' end of mRNA in vitro. The -
Synonyms
ERI1;exoribonuclease 1;3-5 exoribonuclease 1;eri-1 homolog;3-5 exonuclease ERI1;enhanced RNAi protein 1;histone mRNA 3-exonuclease 1;three prime histone mRNA exonuclease 1;histone mRNA 3 end-specific exonuclease;Thex1;eri-1;3hexo;3110010F15Rik
Recombinant Proteins
- Human
- Chicken
- Rat
- Zebrafish
- Mouse
- S.cerevisiae
- Ashbya gossypii
- E.coli
- Mammalian Cells
- HEK293
- His
- His&T7
- Non
- Myc&DDK
- His&Fc&Avi
Involved Pathway
ERI1 involved in several pathways and played different roles in them. We selected most pathways ERI1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with ERI1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
ERI1 has several biochemical functions, for example, 3-5 exonuclease activity,3-5-exoribonuclease activity,histone pre-mRNA stem-loop binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ERI1 itself. We selected most functions ERI1 had, and list some proteins which have the same functions with ERI1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| metal ion binding | KDM6BB,HNRNPA0L,ACO1,MYLK,ZNF23,ZNF32,ZEB2A,ZNF556,STEAP1,DTX1 |
| 3-5-exoribonuclease activity | PNPT1,DIS3L,CNOT7,EXOSC7,TOE1,PAN2,SMFN,ERI3,ERI2,USB1 |
| 3-5 exonuclease activity | REXO2,POLG,APLF,POLE,MRE11A,EXD2,RAD1,RAD9B,EXOSC10,TREX1 |
| rRNA binding | RPS5,SBDS,TLR13,MRPS7,FASTKD5,NOL12,RPL9,FASTKD2,MRPL20,MTERFD2 |
| ribosome binding | ICT1,CPEB4,EIF2S1B,EIF5A,CPEB1B,MTRF1L,ETF1B,EIF3K,SEC61A1,EIF2S1A |
| histone pre-mRNA stem-loop binding | SLBP |
Interacting Protein
ERI1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ERI1 here. Most of them are supplied by our site. Hope this information will be useful for your research of ERI1.
ssrna_cg;SYN1;Eif3a;Eif3e;Ppp2ca;Cep78;Naa50;Topbp1;Cdc16;CDCA5;CEP170P1
Resources
Related Services
Related Products
References
- Zhang, QF; Siegel, TN; et al. Exonuclease-mediated degradation of nascent RNA silences genes linked to severe malaria. NATURE 513:431-+(2014).
- Shimoyama, Y; Morikawa, Y; et al. Identification of human SEP1 as a glial cell line-derived neurotrophic factor-inducible protein and its expression in the nervous system. NEUROSCIENCE 121:899-906(2003).
