ENTPD8
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Official Full Name
ectonucleoside triphosphate diphosphohydrolase 8 -
Synonyms
ENTPD8;ectonucleoside triphosphate diphosphohydrolase 8;GLSR2492;NTPDase 8;UNQ2492;E NTPDase 8;EC 3.6.1.5;iver ecto ATP diphosphohydrolase;NTPDase8;E-NTPDase 8;ecto-ATP-diphosphohydrolase;liver ecto-ATP-diphosphohydrolase;nucleoside triphosphate diphosphohydrolase-8;NTPDase-8
Recombinant Proteins
- Rat
- Human
- Mouse
- Zebrafish
- Chicken
- Bovine
- Mammalian Cells
- Wheat Germ
- HEK293
- In Vitro Cell Free System
- E.coli
- His
- GST
- Non
- Avi
- Fc
- DDK
- Myc
Involved Pathway
ENTPD8 involved in several pathways and played different roles in them. We selected most pathways ENTPD8 participated on our site, such as Epstein-Barr virus infection,Purine metabolism,Pyrimidine metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with ENTPD8 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Pyrimidine metabolism | DCK,TYMP,POLR1A,CTPS2,POLR2D,POLR3A,NME1-NME2,CMPK1,POLR2K,NME4 |
| Purine metabolism | ITPA,AK4,PDE4C,NTPCR,CECR1A,PNPT1,PRIM1,ADSS,ADSL,PDE6D |
| Epstein-Barr virus infection | RELB,HDAC4,TRAF6,AKT1,EP300,POLR3B,PSMD3,HSPB1,NFKBIA,RAN |
Protein Function
ENTPD8 has several biochemical functions, for example, ATP binding,metal ion binding,nucleoside-diphosphatase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ENTPD8 itself. We selected most functions ENTPD8 had, and list some proteins which have the same functions with ENTPD8. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| metal ion binding | CAR15,VAV3B,BTR02,GNAL,PM20D1.2,CYP4F14,RC3H2,POGZ,DHX57,THAP3 |
| nucleoside-triphosphatase activity | ENTPD3,DDX3X,ENTPD1,ENTPD6,NTPCR |
| ATP binding | CAMKK1A,PSMC1,WRN,DYRK1B,CHD4A,DDX46,AK1,OASL2,RIPK4,GMPS |
| nucleoside-diphosphatase activity | ENTPD1,ENTPD3,NUDT5 |
Interacting Protein
ENTPD8 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ENTPD8 here. Most of them are supplied by our site. Hope this information will be useful for your research of ENTPD8.
Resources
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References
- Nadel, Y; Lecka, J; et al. Highly Potent and Selective Ectonucleotide Pyrophosphatase/Phosphodiesterase I Inhibitors Based on an Adenosine 5 '-(alpha or gamma)-Thio-(alpha,beta- or beta,gamma)-methylenetriphosphate Scaffold. JOURNAL OF MEDICINAL CHEMISTRY 57:4677-4691(2014).
- Cabiati, M; Caruso, R; et al. Transcriptomic Profiling of the Four Adenosine Receptors in Human Leukocytes of Heart Failure Patients. BIOMED RESEARCH INTERNATIONAL :-(2013).
