ENO3
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Official Full Name
enolase 3 (beta, muscle) -
Overview
This gene encodes one of the three enolase isoenzymes found in mammals. This isoenzyme is found in skeletal muscle cells in the adult where it may play a role in muscle development and regeneration. A switch from alpha enolase to beta enolase occurs in muscle tissue during development in rodents. Mutations in this gene have be associated glycogen storage disease. Alternatively spliced transcript variants encoding different isoforms have been described. -
Synonyms
ENO3;enolase 3 (beta, muscle);enolase 3, (beta, muscle);beta-enolase;muscle-specific enolase;skeletal muscle enolase;2-phospho-D-glycerate hydrolyase;MSE;GSD13
Recombinant Proteins
- Human
- Zebrafish
- Rat
- Mouse
- Chicken
- Rabbit
- Bovine
- E.coli
- Mammalian Cells
- Wheat Germ
- HEK293
- In Vitro Cell Free System
- Yeast
- GST
- His
- Non
- His&Fc
- His&GST
- His&Fc&Avi
- Myc&DDK
- N-His&C-Myc
- N-6xHis
- N-10xHis
Involved Pathway
ENO3 involved in several pathways and played different roles in them. We selected most pathways ENO3 participated on our site, such as Glycolysis / Gluconeogenesis,Metabolic pathways,Carbon metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with ENO3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Biosynthesis of amino acids | CBSB,PYCR1B,ALDOAB,BCAT1,GOT2,ENO1B,ACO1,MAT2AL,TAT,TKT |
| RNA degradation | PFKMA,TOB2,DDX6,PARN,PABPC1,PFKMB,XRN2,NUDT16,PAPD7,PABPC1L2A |
| Glycolysis / Gluconeogenesis | ALDH3B1,ADH1C,ALDH2.2,PFKP,PKM2,ALDOC,PGAM1A,AKR1A1A,PFKL,G6PCA.2 |
| HIF- signaling pathway | PDHA1,MAP2K1,TF,AKT2,PIK3R5,NOX3,PGK1,BCL2,PFKFB3,IL6 |
| Metabolic pathways | MTMR1B,ADI1,C1GALT1C1,PFKL,B3GALT1,NDST2,DMGDH,SDSL,DLAT,PET112L |
| Carbon metabolism | FBP2,MTHFR,AGXT,HK1,PKM,TKT,PRPS1L1,ALDH6A1,PKLR,G6PDX |
Protein Function
ENO3 has several biochemical functions, for example, magnesium ion binding,phosphopyruvate hydratase activity,protein heterodimerization activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ENO3 itself. We selected most functions ENO3 had, and list some proteins which have the same functions with ENO3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein homodimerization activity | LRRFIP1,CDSN,APOA1BP,Il6ra,NAMPT,RENBP,CADM2,MYO7A,TFAP2A,CEACAM5 |
| protein heterodimerization activity | UGT1A4,HIF1A,SYT14,HIST1H4H,KATNA1,H3F3B.1,RBP4,THRA,ALG2,FLOT1 |
| phosphopyruvate hydratase activity | ENO1,ENO4,ENO2,GM5506,ENO1B,ENO1A |
| magnesium ion binding | THG1L,PRTFDC1,RPS6KA3B,NIM1K,HPGDS,PRPS2,IMPA2,RRAGC,ABL2,SNRK |
Interacting Protein
ENO3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ENO3 here. Most of them are supplied by our site. Hope this information will be useful for your research of ENO3.
PDE4DIP;TCAP;KALRN;SNAPIN;ALDOA;TRAPPC2;SPTB;PKM;DSP;NEB;PGM1;MAN2A2;SGCG;DCTN1;MTMR14;TTN;Cep152;e3_vaccw
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