EMG1
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Official Full Name
EMG1 nucleolar protein homolog (S. cerevisiae) -
Overview
This gene encodes an essential, conserved eukaryotic protein involved in ribosome biogenesis. In yeast, the related protein is a component of the small subunit processome and is essential for biogenesis of the ribosomal 40S subunit. A mutation in this gene has been associated with Bowen-Conradi syndrome. -
Synonyms
EMG1;EMG1 nucleolar protein homolog (S. cerevisiae);ribosomal RNA small subunit methyltransferase NEP1;C2F;Grcc2f;NEP1;18S rRNA (pseudouridine-N1-)-methyltransferase NEP1;18S rRNA Psi1248 methyltransferase;C2f protein;EMG 1;EMG1 nucleolar protein homolog (S cerevisiae);essential for mitotic growth 1;FLJ60792;NEP1_HUMAN;Nucleolar protein EMG1 homolog;Protein C2f;Ribosome biogenesis protein NEP1
Recombinant Proteins
- Human
- Rhesus macaque
- Zebrafish
- Mouse
- Chicken
- E.coli
- Mammalian Cells
- Wheat Germ
- HEK293
- In Vitro Cell Free System
- His
- GST
- Non
- Myc&DDK
- His&Fc&Avi
Involved Pathway
EMG1 involved in several pathways and played different roles in them. We selected most pathways EMG1 participated on our site, such as Ribosome biogenesis in eukaryotes, which may be useful for your reference. Also, other proteins which involved in the same pathway with EMG1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Ribosome biogenesis in eukaryotes | GTPBP4,NOB1,RIOK2,NHP2L1A,FBL,RAN,PWP2,XPO1,NXT2,WDR36 |
Protein Function
EMG1 has several biochemical functions, for example, RNA binding,poly(A) RNA binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by EMG1 itself. We selected most functions EMG1 had, and list some proteins which have the same functions with EMG1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | RAB10,CAMTA2,PBX2,FEM1C,GPKOW,FAM50B,PYCARD,FRG1,FOXB1,TBC1D10C |
| rRNA binding | KDM2B,RPS5,RPF2,RPS9,FASTKD5,MRPL20,RPS4Y2,MRPS17,RNASEL,TLR13 |
| RNA binding | IFIT8,PTBP1,JAKMIP1,LIN28A,ZFP346,RNASEL4,UMPS,YY1,DDX59,SNRNP70 |
| poly(A) RNA binding | RBM14,FKBP3,RPS4Y1,PSIP1,DDX5,DHX8,MRPS9,TTC6,ZCCHC6,MYH9 |
Interacting Protein
EMG1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with EMG1 here. Most of them are supplied by our site. Hope this information will be useful for your research of EMG1.
FAM74A4;ANXA3;CTSE;HIVEP1;PSME1;KHDRBS1;NAT6;SLC25A38;PSMB7;ssrna_ug
Resources
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References
- Sondalle, SB; Baserga, SJ; et al. Human diseases of the SSU processome. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE 1842:758-764(2014).
- Peifer, C; Sharma, S; et al. Yeast Rrp8p, a novel methyltransferase responsible for m(1)A 645 base modification of 25S rRNA. NUCLEIC ACIDS RESEARCH 41:1151-1163(2013).
