EMD
-
Official Full Name
EMD emerin -
Overview
Emerin is a serine-rich nuclear membrane protein and a member of the nuclear lamina-associated protein family. It mediates membrane anchorage to the cytoskeleton. Dreifuss-Emery muscular dystrophy is an X-linked inherited degenerative myopathy resulting from mutation in the emerin gene. -
Synonyms
EMD;emerin;Emery Dreifuss muscular dystrophy;LEM domain containing 5;LEMD5;STA;EDMD
Recombinant Proteins
- Rat
- Human
- Mouse
- Mus musculus
- Mammalian Cells
- Wheat Germ
- HEK293
- In Vitro Cell Free System
- E.coli
- His
- Non
- GST
- Myc&DDK
- His&Fc&Avi
Involved Pathway
EMD involved in several pathways and played different roles in them. We selected most pathways EMD participated on our site, such as Hypertrophic cardiomyopathy (HCM),Arrhythmogenic right ventricular cardiomyopathy (ARVC),Dilated cardiomyopathy, which may be useful for your reference. Also, other proteins which involved in the same pathway with EMD were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Dilated cardiomyopathy | CACNG1,ITGA10,MYL3,TPM4,SGCG,CACNA2D1,SGCD,DES,ACTC1,ITGB4 |
| Arrhythmogenic right ventricular cardiomyopathy (ARVC) | ITGAV,CACNG3,SGCG,CACNA2D4,Itga10&Itgb1,ITGA9,ITGB5,DSP,CACNG8,TCF7 |
| Hypertrophic cardiomyopathy (HCM) | ATP2A2,CACNA2D2,ITGA8,CACNB2,LMNA,SGCD,ITGA7,PRKAB1,SGCA,PRKAA1 |
Protein Function
EMD has several biochemical functions, for example, actin binding,beta-tubulin binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by EMD itself. We selected most functions EMD had, and list some proteins which have the same functions with EMD. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| actin binding | DMTN,NF2A,MYH7,EPB41L1,MSRB1A,VMHCL,WASH1,CAPZB,MICAL1,SHROOM3 |
| beta-tubulin binding | RACGAP1,OST4,GABARAPL2,UXT,AKAP1,CCT5,RANBP10,SPAST,MAP1S,GABARAP |
| protein binding | IL5,GCA,DHX38,IGHMBP2,CMTM3,SEMA4C,DISC1,ARFIP2,MRPL15,CP110 |
Interacting Protein
EMD has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with EMD here. Most of them are supplied by our site. Hope this information will be useful for your research of EMD.
FATE1;CTNNB1;BCLAF1;SYNE2;TRIM42;80125
Resources
Related Services
Related Products
References
- van den Heuvel, MM; Verheij, M; et al. NHS-IL2 combined with radiotherapy: preclinical rationale and phase Ib trial results in metastatic non-small cell lung cancer following first-line chemotherapy. JOURNAL OF TRANSLATIONAL MEDICINE 13:-(2015).
