ELMO2
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Official Full Name
engulfment and cell motility 2 -
Overview
The protein encoded by this gene interacts with the dedicator of cyto-kinesis 1 protein. Similarity to a C. elegans protein suggests that this protein may function in phagocytosis of apoptotic cells and in cell migration. Alternative splicing results in multiple transcript variants encoding the same protein. -
Synonyms
ELMO2;engulfment and cell motility 2;engulfment and cell motility 2 (ced 12 homolog, C. elegans);engulfment and cell motility protein 2;CED 12;CED12;ELMO 2;FLJ11656;KIAA1834;Ced 12 homolog 2;CED 12 homolog A;CED 12A;CED12 homolog A;CED12A;hCED 12A;hCED12A;PH domain protein CED12A;Protein ced 12 homolog A;hCed-12A;ced-12 homolog 2;OTTHUMP00000031762;OTTHUMP00000031764;OTTHUMP00000031765;protein ced-12 homolog A;CED-12;ELMO-2
Recombinant Proteins
- Human
- Rhesus macaque
- Mouse
- Zebrafish
- E.coli
- Mammalian Cell
- Wheat Germ
- HEK293
- HEK293T
- In Vitro Cell Free System
- His
- GST
- Non
- His&Fc&Avi
- Myc&DDK
Involved Pathway
ELMO2 involved in several pathways and played different roles in them. We selected most pathways ELMO2 participated on our site, such as Bacterial invasion of epithelial cells,Shigellosis, which may be useful for your reference. Also, other proteins which involved in the same pathway with ELMO2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Shigellosis | UBE2D2,WASL,WASF1,MAPK11,PFN2,WAS,ITGA5,RELA,IL-8,ITGB1 |
| Bacterial invasion of epithelial cells | ELMO1,ARPC2,PIK3R3,SHC2,SRC,SHC4,DNM1,FN1,CRKL,DOCK1 |
Protein Function
ELMO2 has several biochemical functions, for example, SH3 domain binding,protein binding,receptor tyrosine kinase binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ELMO2 itself. We selected most functions ELMO2 had, and list some proteins which have the same functions with ELMO2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | TELO2,ATXN3,NOX5,CDK7,ITGB1BP3,IMPA1,PABPC4,MTRR,RAB41,GRIN2C |
| receptor tyrosine kinase binding | GAS6,MYOC,GNB2L1,LRP4,CPNE3,FLT3LG,PTPN11,SHC4,DOCK4,ZNF259 |
| SH3 domain binding | CASP9,HCLS1,WAS,PLSCR1,DOCK4,SGIP1,ADAM12,PARK2,INPPL1B,MAPT |
Interacting Protein
ELMO2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ELMO2 here. Most of them are supplied by our site. Hope this information will be useful for your research of ELMO2.
GRB2
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