EIF3J
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Official Full Name
eukaryotic translation initiation factor 3, subunit J -
Overview
Eukaryotic initiation factor-3 (EIF3) has a molecular mass of about 600 kD and contains 13 nonidentical protein;subunits, including EIF3J. EIF3 plays a central role in binding of initiator methionyl-tRNA and mRNA to the 40S;ribosomal subunit to form the 40S initiation complex (Fraser et al., 2004 (PubMed 14688252); Fraser et al., 2007;(PubMed 17588516)). -
Synonyms
EIF3J;eukaryotic translation initiation factor 3, subunit J;EIF3S1, eukaryotic translation initiation factor 3, subunit 1 alpha, 35kDa;eukaryotic translation initiation factor 3 subunit J;eIF3 alpha;eIF3 p35;eIF-3-alpha;eukaryotic translati
Recombinant Proteins
- Human
- Rhesus macaque
- Chicken
- Rat
- E.coli
- Mammalian Cells
- Wheat Germ
- Human
- HEK293
- In Vitro Cell Free System
- GST
- His
- Non
- His&Fc&Avi
Involved Pathway
EIF3J involved in several pathways and played different roles in them. We selected most pathways EIF3J participated on our site, such as RNA transport, which may be useful for your reference. Also, other proteins which involved in the same pathway with EIF3J were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| RNA transport | NUP160,NXF1,TRNT1,EIF3EA,MAGOH2,SUMO2,EIF3BA,SUMO3B,THOC2,NUP62 |
Protein Function
EIF3J has several biochemical functions, for example, protein binding,translation initiation factor activity,contributes_to translation initiation factor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by EIF3J itself. We selected most functions EIF3J had, and list some proteins which have the same functions with EIF3J. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | SUPV3L1,ANXA4,NOTCH4,NAPG,SRSF7,N6AMT1,CSTF2,FAH,CPNE1,SYN1 |
| translation initiation factor activity | EIF2S3,EIF1AXB,EIF3HA,EIF4A1A,EIF4H,EIF5,EIF1AX,EIF3S10,EIF4E2,EIF1AY |
| contributes_to translation initiation factor activity | EIF3L,EIF2B4,EIF3I,EIF3EA,EIF3B,EIF3S10,EIF2B5,EIF2B3,EIF3BA,EIF3M |
Interacting Protein
EIF3J has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with EIF3J here. Most of them are supplied by our site. Hope this information will be useful for your research of EIF3J.
EIF3B;CSNK2A1;Eif3a;EIF4G1;EIF3H;EIF4G2;GNB5;TADA3;TPD52L1;GOLM1;MAGED1;bosutinib;imatinib
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References
- Aylett, CHS; Boehringer, D; et al. Structure of a Yeast 40S-eIF1-eIF1A-eIF3-eIF3j initiation complex. NATURE STRUCTURAL & MOLECULAR BIOLOGY 22:269-271(2015).
- Rezende, AM; Assis, LA; et al. The translation initiation complex eIF3 in trypanosomatids and other pathogenic excavates - identification of conserved and divergent features based on orthologue analysis. BMC GENOMICS 15:-(2014).
