Ebf4
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Official Full Name
Early B-Cell Factor 4 -
Overview
B cells or B lymphocytes are a type of lymphocyte in the humoral immunity of the adaptive immune system. B cells can be distinguished from other lymphocytes, such as T cells and natural killer cells (NK cells), by the presence of a protein on the B cells outer surface known as a B cell receptor (BCR). This specialized receptor protein allows a B cell to bind to a specific antigen. In birds, B cells mature in the bursa of Fabricius. In mammals, immature B cells are formed in the bone marrow. -
Synonyms
Early B-Cell Factor 4;EBF4
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| EBF4-3023H | Recombinant Human EBF4 Protein, GST-tagged | Wheat Germ | Human | GST |
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| EBF4-1537HCL | Recombinant Human EBF4 cell lysate | Human | Non |
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| EBF4-2537H | Recombinant Human EBF4 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293 | Human | Myc&DDK |
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| Ebf4-2712M | Recombinant Mouse Ebf4 Protein, Myc/DDK-tagged | HEK293 | Mouse | Myc&DDK |
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| EBF4-4143HF | Recombinant Full Length Human EBF4 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 88 amino acids |
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Involved Pathway
Ebf4 involved in several pathways and played different roles in them. We selected most pathways Ebf4 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with Ebf4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
Ebf4 has several biochemical functions, for example, DNA binding,metal ion binding,protein dimerization activity. Some of the functions are cooperated with other proteins, some of the functions could acted by Ebf4 itself. We selected most functions Ebf4 had, and list some proteins which have the same functions with Ebf4. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding | MEF2B,POU2F3,FOSB,RFX4,ATF2,SREBF1,SMAD2,RBPJ,POU4F3,MZF1 |
| DNA binding | DMBX1,ZNF23,HOXC6A,ILF3,H2AFV,HER6,ZNF157,PAX6B,ANG,ZNF280C |
| metal ion binding | GM5077,HECTD1,CYP8B1,Car4,KARS,ATP8B1,ZC3H8,KEX2,ZNF609A,ADCY7 |
| protein dimerization activity | NPAS1,HER8A,NEUROG2,FIGLA,PRKRIR,NUP210,SOHLH1,MITFA,ZBED1,PEF1 |
Interacting Protein
Ebf4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Ebf4 here. Most of them are supplied by our site. Hope this information will be useful for your research of Ebf4.
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References
- Kwun, J; Page, E; et al. Neutralizing BAFF/APRIL With Atacicept Prevents Early DSA Formation and AMR Development in T Cell Depletion Induced Nonhuman Primate AMR Model. AMERICAN JOURNAL OF TRANSPLANTATION 15:815-822(2015).
- Bone, RN; Gai, Y; et al. Inhibition of Ca2+-Independent Phospholipase A(2)beta (iPLA(2)beta) Ameliorates Islet Infiltration and Incidence of Diabetes in NOD Mice. DIABETES 64:541-554(2015).
