DSCAM
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Official Full Name
Down syndrome cell adhesion molecule -
Overview
The Dscam family of cell surface proteins mediates recognition events between neurons that play an essential role in the establishment of neural circuits in many organisms. Interneurons form synaptic connections with retinal ganglion cells in specific layers. Dscam and DscamL are expressed in different subsets of interneurons and ganglion cells. Interestingly, interneurons and ganglion cells that target to the same layer, express the same Dscam protein. -
Synonyms
DSCAM;Down syndrome cell adhesion molecule;Down syndrome cell adhesion molecule homolog;4932410A21Rik
Recombinant Proteins
- Human
- Rat
- Mouse
- E.coli
- Mammalian Cells
- Wheat Germ
- HEK293
- His
- Non
- GST
- Avi&Fc&His
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| DSCAM-12170H | Recombinant Human DSCAM, His-tagged | E.coli | Human | His | C-term-100a.a. | |
| DSCAM-1000H |
Active Recombinant Human DSCAM
|
Mammalian Cells | Human | Non | Glu18-Met1595 |
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| DSCAM-1961R | Recombinant Rat DSCAM Protein | Mammalian Cells | Rat | His |
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| DSCAM-2882H | Recombinant Human DSCAM Protein, GST-tagged | Wheat Germ | Human | GST |
|
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| DSCAM-4834M | Recombinant Mouse DSCAM Protein | Mammalian Cells | Mouse | His |
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| DSCAM-1620R | Recombinant Rat DSCAM Protein, His (Fc)-Avi-tagged | HEK293 | Rat | Avi&Fc&His |
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| DSCAM-1620R-B | Recombinant Rat DSCAM Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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| DSCAM-2535M | Recombinant Mouse DSCAM Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | Avi&Fc&His |
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| DSCAM-2535M-B | Recombinant Mouse DSCAM Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| DSCAM-4388H | Recombinant Human DSCAM Protein, His (Fc)-Avi-tagged | HEK293 | Human | Avi&Fc&His |
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| DSCAM-4388H-B | Recombinant Human DSCAM Protein Pre-coupled Magnetic Beads | HEK293 | Human |
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Involved Pathway
DSCAM involved in several pathways and played different roles in them. We selected most pathways DSCAM participated on our site, such as Cell-Cell communication,DSCAM interactions,FOXA1 transcription factor network, which may be useful for your reference. Also, other proteins which involved in the same pathway with DSCAM were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| DSCAM interactions | DSCAMA,DSCAML1,DCC |
| Cell-Cell communication | SKAP2,CDH12,CDH6,CADM2A,DSCAMA,CDH17,KIRREL,CDH13,CADM2B,COL17A1A |
| FOXA1 transcription factor network | NFIA,NFIB,FOXA1,NFIC,CC10,NRIP1,CEBPB,AP1B1,NR2F2,TFF1 |
Protein Function
DSCAM has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DSCAM itself. We selected most functions DSCAM had, and list some proteins which have the same functions with DSCAM. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | CTAGE5,DACT2,MAPK10,SRMS,UNC119B,ELAVL2,ZNF625,DPCD,ABI1,NGFRB |
Interacting Protein
DSCAM has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DSCAM here. Most of them are supplied by our site. Hope this information will be useful for your research of DSCAM.
Resources
Related Services
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References
- Ng, TH; Chiang, YA; et al. Review of Dscam-mediated immunity in shrimp and other arthropods (Reprinted from Dev Comp Immunol, vol 46, pg 129-138, 2014). DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY 48:306-314(2015).
- Ng, TH; Chiang, YA; et al. Review of Dscam-mediated immunity in shrimp and other arthropods. DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY 46:129-138(2014).
