DOK4
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Official Full Name
docking protein 4 -
Overview
Docking protein 4 is a protein that in humans is encoded by the DOK4 gene. -
Synonyms
DOK4;docking protein 4;FLJ10488;IRS5;IRS-5;insulin receptor substrate 5;downstream of tyrosine kinase 4
Recombinant Proteins
- Human
- Rhesus macaque
- Mouse
- E.coli
- Mammalian Cell
- Wheat Germ
- HEK293
- In Vitro Cell Free System
- GST
- His
- Non
- His&Fc&Avi
Involved Pathway
DOK4 involved in several pathways and played different roles in them. We selected most pathways DOK4 participated on our site, such as Signaling events regulated by Ret tyrosine kinase, which may be useful for your reference. Also, other proteins which involved in the same pathway with DOK4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Signaling events regulated by Ret tyrosine kinase | GFRA1,GDNF,DOK5,DOK6,PDLIM7 |
Protein Function
DOK4 has several biochemical functions, for example, insulin receptor binding,protein binding,receptor signaling protein activity. Some of the functions are cooperated with other proteins, some of the functions could acted by DOK4 itself. We selected most functions DOK4 had, and list some proteins which have the same functions with DOK4. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| receptor signaling protein activity | IL1RL1,PLCE1,NGF,FCAR,IL4R,DAXX,CD19,cgr2b,RAF1B,KLK1B4 |
| protein binding | SERPINI2,MELK,NEDD9,CDC42,MED8,WASH1,TMEM14C,LGALS9C,ARMC2,MXD4 |
| insulin receptor binding | IGF1R,DOK7,PHIP,PIK3R1,GRB10,IGF1,SLC2A2,INS1,SNX2,DOK2 |
Interacting Protein
DOK4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DOK4 here. Most of them are supplied by our site. Hope this information will be useful for your research of DOK4.
OPRM1;DOK3;CCM2;STAT2;PTK2;EGFR;ERBB2;LIX1;OLIG1;RBP7
Resources
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References
- Al Olaby, RR; Cocquerel, L; et al. Identification of a Novel Drug Lead That Inhibits HCV Infection and Cell-to-Cell Transmission by Targeting the HCV E2 Glycoprotein. PLOS ONE 9:-(2014).
- Saravanan, S; Pandikumar, P; et al. In Vivo and In Vitro Immunomodulatory Potential of Swertiamarin Isolated from Enicostema axillare (Lam.) A. Raynal That Acts as an Anti-inflammatory Agent. INFLAMMATION 37:1374-1388(2014).
