DNASE2B

  • Official Full Name

    deoxyribonuclease II beta
  • Overview

    The protein encoded by this gene shares considerable sequence similarity to, and is structurally related to DNase II. The latter is a well characterized endonuclease that catalyzes DNA hydrolysis in the absence of divalent cations at acidic pH. Unlike DNase II which is ubiquitously expressed, expression of this gene product is restricted to the salivary gland and lungs. The gene has been localized to chromosome 1p22.3 adjacent (and in opposite orientation) to the uricase pseudogene. Two transcript variants encoding different isoforms have been described for this gene.
  • Synonyms

    DNASE2B;deoxyribonuclease II beta;deoxyribonuclease-2-beta;DLAD;Deoxyribonuclease 2 beta;Deoxyribonuclease 2 beta precursor;DNase 2 like acid DNase;DNASE 2B;DNase II beta;DNase II like acid DNase;DNASE2;DNase2 like acid DNase;DnaseIIb;EC 3.1.22.1;Endonuclease DLAD;Lysosomal DNase II;UOX;DNase2-like acid DNase;DNase II-like acid DNase

Recombinant Proteins

  • Rat
  • Human
  • Chicken
  • Cynomolgus
  • Mouse
  • Mammalian Cells
  • Wheat Germ
  • HEK293
  • E.coli
  • In Vitro Cell Free System
  • His
  • GST
  • Non
  • His&GST
  • His&Fc&Avi
Cat.# Product name Source (Host) Species Tag Protein Length Price
DNASE2B-1921R Recombinant Rat DNASE2B Protein Mammalian Cells Rat His
DNASE2B-2781H Recombinant Human DNASE2B Protein, GST-tagged Wheat Germ Human GST
DNASE2B-3307C Recombinant Chicken DNASE2B Mammalian Cells Chicken His
DNASE2B-471C Recombinant Cynomolgus DNASE2B Protein, His-tagged Mammalian Cells Cynomolgus His
DNASE2B-4731M Recombinant Mouse DNASE2B Protein Mammalian Cells Mouse His
DNASE2B-6862HCL Recombinant Human DNASE2B 293 Cell Lysate HEK293 Human Non
Dnase2b-1359R Recombinant Rat Dnase2b Protein, His&GST-tagged E.coli Rat His&GST Thr23-Asn356
DNASE2B-1580R Recombinant Rat DNASE2B Protein, His (Fc)-Avi-tagged HEK293 Rat His&Fc&Avi
DNASE2B-1580R-B Recombinant Rat DNASE2B Protein Pre-coupled Magnetic Beads HEK293 Rat
DNASE2B-217C Recombinant Cynomolgus Monkey DNASE2B Protein, His (Fc)-Avi-tagged HEK293 Cynomolgus His&Fc&Avi
DNASE2B-217C-B Recombinant Cynomolgus Monkey DNASE2B Protein Pre-coupled Magnetic Beads HEK293 Cynomolgus
DNASE2B-2466M Recombinant Mouse DNASE2B Protein, His (Fc)-Avi-tagged HEK293 Mouse His&Fc&Avi
DNASE2B-2466M-B Recombinant Mouse DNASE2B Protein Pre-coupled Magnetic Beads HEK293 Mouse
DNASE2B-4037HF Recombinant Full Length Human DNASE2B Protein, GST-tagged In Vitro Cell Free System Human GST Full L. 153 amino acids

    Involved Pathway

    DNASE2B involved in several pathways and played different roles in them. We selected most pathways DNASE2B participated on our site, such as Lysosome, which may be useful for your reference. Also, other proteins which involved in the same pathway with DNASE2B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Lysosome TPP1,HEXB,GGA1,DNASE2A,GALC,ARSA,GBA,CTSSB.2,CTSO,MANBA

    Protein Function

    DNASE2B has several biochemical functions, for example, deoxyribonuclease II activity. Some of the functions are cooperated with other proteins, some of the functions could acted by DNASE2B itself. We selected most functions DNASE2B had, and list some proteins which have the same functions with DNASE2B. You can find most of the proteins on our site.

    Function Related Protein
    deoxyribonuclease II activity DNASE2A,DNASE2

    Interacting Protein

    DNASE2B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DNASE2B here. Most of them are supplied by our site. Hope this information will be useful for your research of DNASE2B.

    Resources

    References

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