DIO1
-
Official Full Name
deiodinase, iodothyronine, type I -
Synonyms
DIO1;deiodinase, iodothyronine, type I;TXDI1;type I iodothyronine deiodinase;DIOI;type 1 DI;type-I 5-deiodinase;thyroxine deiodinase type I (selenoprotein);5DI;MGC130050;MGC130051
Recombinant Proteins
- Zebrafish
- Rat
- Human
- Chicken
- Mouse
- Sus scrofa (Pig)
- Dog
- Mus musculus
- Oryctolagus cuniculus (Rabbit)
- Felis catus
- Xenopus laevis
- Suncus murinus (Asian house shrew) (Musk shrew)
- Mammalian Cells
- Wheat Germ
- E.coli
- HEK293
- In Vitro Cell Free System
- His
- GST
- His&Fc&Avi
Involved Pathway
DIO1 involved in several pathways and played different roles in them. We selected most pathways DIO1 participated on our site, such as Thyroid hormone signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with DIO1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Thyroid hormone signaling pathway | MED12,MED17,MAP2K1,FXYD2,WNT4,ATP1B3,PFKFB2,ATP1A1,NCOR1,PLCD1 |
Protein Function
DIO1 has several biochemical functions, for example, oxidoreductase activity,selenium binding,thyroxine 5-deiodinase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by DIO1 itself. We selected most functions DIO1 had, and list some proteins which have the same functions with DIO1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| thyroxine 5-deiodinase activity | DIO2,DIO3,DIO3B,DIO3A |
| selenium binding | SELENBP1,DIO2,GPX3,SEP15,SELT,SEPP1,SELENBP2,RPH3A,GPX1 |
| oxidoreductase activity | ALDH9A1A.1,CYP2C54,CYP2X10.2,C1orf43,DHRS3A,AKR1C6,TDH,SCDB,CYP2C70,AIFM4 |
Interacting Protein
DIO1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DIO1 here. Most of them are supplied by our site. Hope this information will be useful for your research of DIO1.
Resources
Related Services
Related Products
References
