DDX4
-
Official Full Name
DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 -
Overview
DDX4 is an ATP-dependent DEAD-box RNA helicase found in the chromatoid body of the germ cells. This enzyme is specific to germ cells and is necessary for germ cell development. Mouse DDX4 was shown to interact with Dicer suggesting a role in microRNA-medi -
Synonyms
DDX4;DEAD (Asp-Glu-Ala-Asp) box polypeptide 4;DEAD/H (Asp Glu Ala Asp/His) box polypeptide 4;probable ATP-dependent RNA helicase DDX4;VASA;vasa homolog;DEAD box protein 4;DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 4;MGC111074
Recombinant Proteins
- Human
- Rhesus macaque
- Rat
- Cynomolgus
- Chicken
- Zebrafish
- Mouse
- E.coli
- Mammalian Cell
- Wheat Germ
- HEK293
- E. coli
- HEK293T
- In Vitro Cell Free System
- Mammalian cells
- GST
- His
- Myc&DDK
- Non
- His&Fc&Avi
- Flag
Involved Pathway
DDX4 involved in several pathways and played different roles in them. We selected most pathways DDX4 participated on our site, such as Gene Expression,Gene Silencing by RNA,PIWI-interacting RNA (piRNA) biogenesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with DDX4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| PIWI-interacting RNA (piRNA) biogenesis | MAEL,ASZ1,HENMT1,PIWIL4,PLD6,FKBP6,MYBL1,TDRD1 |
| Gene Silencing by RNA | PIWIL4,BARHL1,TDRD1,FKBP6,DPY19L2,TNRC6B,IPO8,EIF2C3,MAEL,TSN |
| Gene Expression | ZNF23,TSEN54,DGCR8,ZNF100,SMARCA5,IPO8,ZNF713,ZNF597,ZNF486,COBRA1 |
Protein Function
DDX4 has several biochemical functions, for example, ATP binding,ATP-dependent RNA helicase activity,nucleic acid binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DDX4 itself. We selected most functions DDX4 had, and list some proteins which have the same functions with DDX4. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ATP-dependent RNA helicase activity | DDX25,DDX49,DHX32,DDX50,TMEM38A,DDX41,DHX8,DDX55,ACTG2,DDX56 |
| ATP binding | MYH1E,MAPK8,MERTK,PIM1,NME2A,TAP2,BMP2K,UBE2J2,RECQL4,JAK2A |
| nucleic acid binding | RBM4.1,ANG4,TARDBPL,GFI1AA,ZFP553,SMFN,SRSF6B,Akap17b,ZXDB,ZSCAN10 |
Interacting Protein
DDX4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DDX4 here. Most of them are supplied by our site. Hope this information will be useful for your research of DDX4.
SRC;N;USE1
Resources
Related Services
Related Products
References
