DDAH2

  • Official Full Name

    Dimethylarginine Dimethylaminohydrolase 2

  • Overview

    This gene belongs to the dimethylarginine dimethylaminohydrolase (DDAH) gene family. The encoded enzyme plays a role in nitric oxide generation by regulating cellular concentrations of methylarginines, which in turn inhibit nitric oxide synthase activity.

  • Synonyms

    N(G),N(G)-dimethylarginine dimethylaminohydrolase 2;dime-thylarginine dimethylaminohydrolase 2;DDAH-2;DDAH;DDAH2;protein G6a;S-phase protein;dimethylargininase-2;NG30;G6a;dimethylarginine dimethylaminohydrolase II;NG-dimethylarginine dimethylamino hydrolase homolog;dimethylarginine dimethylaminohydrolase 2;OT-THUMP00000029307;OTTHUMP00000029308;OT-THUMP00000029310;OTTHUMP00000174406;OT-THUMP00000174488;OTTHUMP00000174489;EC 3.5.3.18;alternative name: NG30, G6a

Recombinant Proteins

  • Human
  • Rhesus macaque
  • Rat
  • Mouse
  • Zebrafish
  • E.coli
  • Mammalian Cell
  • Wheat Germ
  • HEK293
  • In Vitro Cell Free System
  • E. coli
  • His
  • GST
  • Non
  • His&Fc&Avi
  • N-His-GST
Cat.# Product name Source (Host) Species Tag Protein Length Price
DDAH2-11876H Recombinant Human DDAH2, His-tagged E.coli Human His 1-285a.a.
DDAH2-1203R Recombinant Rhesus monkey DDAH2 Protein, His-tagged Mammalian Cell Rhesus macaque His
DDAH2-1809R Recombinant Rat DDAH2 Protein Mammalian Cell Rat His
DDAH2-2429H Recombinant Human DDAH2 Protein, GST-tagged Wheat Germ Human GST
DDAH2-26260TH Recombinant Human DDAH2, His-tagged E.coli Human His 71-261 a.a.
DDAH2-4380M Recombinant Mouse DDAH2 Protein Mammalian Cell Mouse His
DDAH2-5853Z Recombinant Zebrafish DDAH2 Mammalian Cell Zebrafish His
DDAH2-449HCL Recombinant Human DDAH2 cell lysate Human Non
DDAH2-1028R Recombinant Rhesus Macaque DDAH2 Protein, His (Fc)-Avi-tagged HEK293 Rhesus macaque His&Fc&Avi
DDAH2-1028R-B Recombinant Rhesus Macaque DDAH2 Protein Pre-coupled Magnetic Beads HEK293 Rhesus macaque
DDAH2-1467R Recombinant Rat DDAH2 Protein, His (Fc)-Avi-tagged HEK293 Rat His&Fc&Avi
DDAH2-1467R-B Recombinant Rat DDAH2 Protein Pre-coupled Magnetic Beads HEK293 Rat
DDAH2-2067H Recombinant Human DDAH2 Protein (Ala31-Leu265), N-His tagged E.coli Human His Ala31-Leu265
DDAH2-2250M Recombinant Mouse DDAH2 Protein, His (Fc)-Avi-tagged HEK293 Mouse His&Fc&Avi
DDAH2-2250M-B Recombinant Mouse DDAH2 Protein Pre-coupled Magnetic Beads HEK293 Mouse
DDAH2-2426HF Recombinant Full Length Human DDAH2 Protein, GST-tagged In Vitro Cell Free System Human GST Full L. 285 amino acids
DDAH2-3193H Recombinant Human DDAH2 protein(1-285aa), His-GST-tagged E. coli Human N-His-GST 1-285aa

    Involved Pathway

    DDAH2 involved in several pathways and played different roles in them. We selected most pathways DDAH2 participated on our site, such as Metabolism,Metabolism of nitric oxide,eNOS activation, which may be useful for your reference. Also, other proteins which involved in the same pathway with DDAH2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    eNOS activation CYGB,CYGB1,ZDHHC21,DDAH1,LYPLA1,CYGB2
    Metabolism of nitric oxide CYGB2,DDAH1,NOSIP,CYGB,CYGB1,GCHFR,NOSTRIN,LYPLA1,SPRB,ZDHHC21
    eNOS activation and regulation NOSIP,CYGB1,CYGB2,CYGB,NOSTRIN,LYPLA1,ZDHHC21,GCHFR,DDAH1,SPRB
    Metabolism SLC27A2A,D2HGDH,SAT1B,GYG1B,SLC25A10,ZDHHC21,CYP2A7,COX6B1,VAPB,SURF1

    Protein Function

    DDAH2 has several biochemical functions, for example, amino acid binding,catalytic activity,dimethylargininase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by DDAH2 itself. We selected most functions DDAH2 had, and list some proteins which have the same functions with DDAH2. You can find most of the proteins on our site.

    Function Related Protein
    amino acid binding TPH2,DDC,AARS2,GCHFR,GOT2,PAH,TAT,DDAH1,TDO2,KARS
    dimethylargininase activity DDAH1
    catalytic activity AOX3L1,CKMT2A,RAG1,ACSL3A,CWF19L1,FPGT,PFKMB,SLC3A2,HSD17B1,APOBEC2B
    protein binding G3BP1,LMO2,CCDC88A,MARK3,FLNA,ALG2,AP4B1,MED16,MAGEA11,MYO9B

    Interacting Protein

    DDAH2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DDAH2 here. Most of them are supplied by our site. Hope this information will be useful for your research of DDAH2.

    TRIP13;TNFSF11;RPS6KA5;GADD45G;TK1;ATP1B1;CDK4;RCC1;ANXA7;CDKN1A;RAP1B;STK3;PIN1;RPS6KA1;TSC22D1;SMN1;CDC73;MKNK1

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