CYP4F11

  • Official Full Name

    cytochrome P450, family 4, subfamily F, polypeptide 11

  • Overview

    This gene, CYP4F11, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This gene is part of a cluster of cytochrome P450 genes on chromosome 19. Another member of this family, CYP4F2, is approximately 16 kb away. Alternatively spliced transcript variants encoding the same protein have been found for this gene.

  • Synonyms

    CYP4F11;cytochrome P450, family 4, subfamily F, polypeptide 11;cytochrome P450, subfamily IVF, polypeptide 11;cytochrome P450 4F11;CYPIVF11

Recombinant Proteins

  • Human
  • E.coli
  • Wheat Germ
  • HEK293
  • In Vitro Cell Free System
  • GST
  • Non
  • His
  • SUMO
  • DDK
  • Myc
Cat.# Product name Source (Host) Species Tag Protein Length Price
CYP4F11-11789H Recombinant Human CYP4F11, GST-tagged E.coli Human GST C-term-350a.a.
CYP4F11-2282H Recombinant Human CYP4F11 Protein, GST-tagged Wheat Germ Human GST
CYP4F11-7103HCL Recombinant Human CYP4F11 293 Cell Lysate HEK293 Human Non
CYP4F11-1130H Recombinant Human CYP4F11 Protein (38-524 aa), His-SUMO-tagged E.coli Human His&SUMO 38-524 aa
CYP4F11-2442HF Recombinant Full Length Human CYP4F11 Protein, GST-tagged In Vitro Cell Free System Human GST Full L. 524 amino acids
CYP4F11-5080H Recombinant Human CYP4F11 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293 Human DDK&Myc
RFL17054HF Recombinant Full Length Human Cytochrome P450 4F11(Cyp4F11) Protein, His-Tagged E.coli Human His Full L. Full Length (1-524)

    Involved Pathway

    CYP4F11 involved in several pathways and played different roles in them. We selected most pathways CYP4F11 participated on our site, such as Arachidonic acid metabolism,Biological oxidations,Cytochrome P450 - arranged by substrate type, which may be useful for your reference. Also, other proteins which involved in the same pathway with CYP4F11 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Metabolism of lipids and lipoproteins SACM1LB,GC,TMEM195,PLD6,ARSJ,NEU3,APOA4B.1,STARD5,ACOT11B,GLTPA
    Fatty acids CYP4A11,CYP2AD2,CYP2A7,CYP4T8,CYP4B1,CYP2F1,CYP2A13,CYP2J2,CYP2D6,CYP2V1
    Miscellaneous substrates CYP2W1,CYP2K18,CYP3C1,CYP2K22,CYP2U1,CYP4B1,CYP2S1,CYP4F22,CYP2K19,CYP2K6
    Cytochrome P450 - arranged by substrate type CYP2A13,CYP7A1,CYP2K17,CYP4F22,CYP2V1,CYP19A1,CYP17A1,CYP11A1,FDXR,CYP3C1
    Eicosanoids CYP4B1,CYP4F12,CYP4F22,CYP4A11
    Metabolism CIAO1,CRYM,PEMT,CYP27B1,LMF2,CYP2Y3,CEPT1,SLC35D2,NDUFA11,DDAH1
    Arachidonic acid metabolism ALOX12E,CYP2J2,DPEP2,AKR1C21,AWAT2,CYP2V1,CYP2P9,DPEP1,ALOX5AP,PLA2G1B
    Biological oxidations CES1,CYP7A1,CYP2K8,POMCB,NCOA2,ADH7,GLYATL1,CYP2B6,GGT6,CYP24A1

    Protein Function

    CYP4F11 has several biochemical functions, for example, heme binding,iron ion binding,oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen. Some of the functions are cooperated with other proteins, some of the functions could acted by CYP4F11 itself. We selected most functions CYP4F11 had, and list some proteins which have the same functions with CYP4F11. You can find most of the proteins on our site.

    Function Related Protein
    oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen CYP11B1,CYP2E1,POR,CYP11B2,CYP4F18,MICAL2,MTRR,CYP11A1,CYP11C1,COQ6
    heme binding CYP3A43,CYP11C1,BACH1,NOS1,CYP24A1,XGB,CYP3A25,CYP27A1,CYP46A1.3,CYP1A1
    iron ion binding CYP2AA4,CYP2X10.2,AOX4,SC4MOL,CYP2C8,CYP2N13,CYP2D10,CYP3A4,ALOX5,PAH

    Interacting Protein

    CYP4F11 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CYP4F11 here. Most of them are supplied by our site. Hope this information will be useful for your research of CYP4F11.

    POT1

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